What are the responsibilities and job description for the Intern, Quantitative Pharmacology position at Denali Therapeutics Inc?
Neurodegenerative diseases are one of the largest medical challenges of our time. Denali Therapeutics is a biotechnology company dedicated to developing breakthrough therapies for neurodegenerative diseases through our deep commitment to degeneration biology and principles of translational medicine. Denali is founded on the collaboration of leading scientists, industry experts, and investors who share the vision that scientific discovery energetically applied to translational medicine is the key to delivering effective therapies to patients.
We invite you to consider an opportunity with Denali to help achieve our goal of delivering meaningful therapeutics to patients.
The Opportunity
Denali is seeking a motivated candidate for an internship position in the Quantitative and Clinical Pharmacology (QCP) team for translational modeling across Denali’s large molecule portfolio.
Responsibilities
Generate preclinical and clinical datasets across programs suitable for platform PK modeling
Develop & apply fit-for-purpose mathematical models (QSP, PK/PD, PBPK) using specialized modeling tools to develop translational insights across Denali’s large molecule portfolio
Document & archive contributions, including data analyses, mathematical models, summary presentations, and reports, to be shareable with other scientists
Present results at cross-functional team meetings and/or poster sessions
Accurate and timely recording of work time by clocking in and out using timekeeping systems
Requirements
Currently pursuing a PhD or PharmD in related scientific field.
Self-motivated, results-driven, organized, resourceful, adaptable and highly collaborative.
Creative thinker with a curious mindset and eager to learn about the complexities of the healthcare and biotech.
Strong analytical and communication skills.
Skilled in mechanistic systems modeling (e.g., differential equations, stochastic methods)
Experience with modeling software or programming languages such as MATLAB/SimBiology, NONMEM, R, Julia, or Python.
Experience in studying PK/PD relationships for biotherapeutics is preferred.
The expected wage for this position based on the South San Francisco California office location is $33.65 per hour. Paid holiday time off is based on Denali's designated holidays. Interns who live more than 50 miles away from the office are eligible for an additional housing stipend.
Job Facts
Start Date: Summer 2025
Length of Assignment: 10 - 12 weeks
Location: South San Francisco, CA
Job Type: Paid Internship
This compensation and benefits information is based on Denali’s good faith estimate as of the date of publication and may be modified in the future.
Denali is committed to its core company value of unity by creating a diverse and inclusive environment. We are proud to be an equal opportunity employer and do not discriminate against any employee or applicant for employment because of race, color, sex, age, national origin, religion, sexual orientation, gender identity and/or expression, status as a veteran, basis of disability, or any other federal, state, or local protected class.
Salary : $34
