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Scientist (Assay Development/rAAV Process/Mammalian Cell Culture/ddPCR/ELISA)

Systems Ally
Worcester, MA Full Time
POSTED ON 12/14/2024
AVAILABLE BEFORE 2/3/2025

100 % onsite

Job Description

  • The Biotherapeutics and Genetic Medicine Group at Company Bioresearch Center in Worcester, MA is seeking a highly motivated scientist for rAAV analytical characterization for gene therapy in a newly established rAAV Research and Production team.
  • The candidate will work collaboratively with our therapeutic area teams to advance Company’s rAAV pipeline.
  • The ideal candidate will have biotechnology experience in rAAV Process and Analytical Development.
  • He/she will be responsible for assisting with the development and execution of analytical methods to support preclinical studies.
  • This position requires a versatile individual, who can work in development and analytical activities to advance pipeline.

Key Responsibilities Include:

  • Assist in the development and application of molecular and cell-based assays (e.g., ELISA, SDS-PAGE, WB, WES, Endotoxin assay)
  • Maintain and culture cells or assist in AAV production as needed
  • Analyze experimental data, generating plots and summarizing results and conclusions
  • Maintain a comprehensive Electronic Lab Notebook documenting experiments
  • Maintain a high level of productivity in the team with clear daily, detailed, and accurate documentation of experiments
  • Collaborate with team members to meet project goals, and advance novel vectors into pipeline
  • Author technical reports and protocols
  • Understand and enforce company culture, teamwork, safety, appropriate handling of materials in an BSL2 environment
  • Perform all activities in compliance with applicable regulations, Company’s policies and guidelines
  • Bring a "can do" spirit to work and deliver on other responsibilities as assigned

Qualifications

Basic:

  • Bachelor's with 2-3 years of experience or Master's in Biology or related discipline
  • Experience in molecular assay development and optimization (e.g., ddPCR, WB, WES, SDS-PAGE)
  • Experience in rAAV production using mammalian cell platforms
  • Experience in cell culture work (e.g., maintenance, transfection, transduction)
  • Ability to work effectively in a highly collaborative and dynamic environment
  • Successful track record of working in high-growth and dynamic organizations
  • Excellent verbal and written communication skills
  • Evidence of "hands-on" experience and expertise
  • Organized and detail oriented with a passion to deliver quality results

What are the top 3-5 skills, experience or education required for this position

  • Bachelor's with 3-5 years of experience or Master's in Biology or related discipline

Job Type: Contract

Pay: $45.00 - $48.00 per hour

Expected hours: 40 per week

Benefits:

  • Commuter assistance
  • Flexible schedule
  • Health insurance
  • Life insurance
  • Paid time off

Schedule:

  • 8 hour shift
  • Day shift
  • Monday to Friday

Education:

  • Bachelor's (Preferred)

Experience:

  • rAAV analytical characterization for gene therap: 3 years (Preferred)
  • rAAV Process and Analytical Development.: 3 years (Preferred)
  • molecular and cell-based assays (e.g., ELISA, SDS-PAGE): 3 years (Preferred)
  • molecular assay development (e.g., ddPCR): 3 years (Preferred)
  • cell culture work (maintenance, transfection, transduction): 3 years (Preferred)

Ability to Commute:

  • Worcester, MA 01602 (Required)

Work Location: In person

Salary : $45 - $48

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