What are the responsibilities and job description for the Senior Principal Scientist, Obesity and/or Cardiometabolic Diseases position at Valo Health?
About Us
Valo Health is a technology company that is integrating human-centric data and AI-powered technology to accelerate the creation of life-changing drugs for more patients faster. Valo was created with the belief that the drug discovery and development process can and should be faster and less expensive, with a much higher probability of success. We are using models early to fail less often, executing clinical trials to add valuation to the company, and generating fit-for-purpose data to feed back into Valo's Opal Computational Platform™ as we reinvent drug discovery and development from the ground up. Disease doesn't wait, so neither can we.
We are a multi-disciplinary team of experts in science, technology, and pharmaceuticals united in our mission to achieve better drugs for patients faster. Valo is committed to hiring diverse talent, prioritizing growth and development, fostering an inclusive environment, and creating opportunities to bring together a group of different experiences, backgrounds, and voices to work together. We achieve the widest-ranging impact when we leverage our broad backgrounds and perspectives to accelerate a new frontier in health. Valo seeks to become the catalyst for the pharmaceutical industry and drive the digital transformation of the industry. Are you ready to join us?
About the Role...
Valo is looking for a Senior Principal Scientists to play a pivotal role in evaluating and prioritizing drug targets for obesity, type 2 diabetes, and cardiovascular diseases identified using Valo's human -centric Opal computational platform. This position requires deep expertise in the biology of obesity or cardiovascular diseases, a background in drug discovery, and a passion for translating human data insights to develop new therapies for complex diseases. You will be responsible for reviewing human evidence discovered using Valo's computational platform and generating expert-driven insights contributing to the prioritization of candidate targets. As target champion and field expert, you will be responsible for delivering target data packages and presenting evidence and rationale for prioritization to internal and external stakeholders. You will contribute to the continuous improvement of the target evaluation and prioritization process by innovating and closely collaborating with subject matter experts, computational scientists, and engineers. You will participate as subject matter expert in the development of research hypotheses that will shape Valo's target discovery strategy.
What You'll Do...
Your primary areas of responsibility will be :
- Comprehensively evaluate candidate targets, including disease associations and druggablity, and develop target data packages
- Generate proposals for target prioritization in close collaboration with data scientists and other subject matter experts
- Provide thought leadership and guidance on obesity, T2D, and cardiovascular diseases biology, staying abreast of emerging trends and advancements in the field
- Generate design proposal and feasibility assessment for target validation using Valo's tissue and cellular disease models in collaboration with Valo's tissue and cell model experts and / or leveraging CRO
- Contribute to improvements of target discovery and prioritization processes
- Provide guidance and feedback on research proposals aimed at discovering targets for obesity or cardiovascular diseases
What You Bring...
You May Also Bring...
More on Valo
Valo Health, LLC ("Valo") is a technology company built to transform the drug discovery and development process using human-centric data and artificial intelligence-driven computation. As a digitally native company, Valo aims to fully integrate human-centric data across the entire drug development life cycle into a single unified architecture, thereby accelerating the discovery and development of life-changing drugs while simultaneously reducing costs, time, and failure rates. The company's Opal Computational Platform™ is an integrated set of capabilities designed to transform data into valuable insights that may accelerate discoveries and enable Valo to advance a robust pipeline of programs across cardiovascular metabolic renal, oncology, and neurodegenerative diseases. Founded by Flagship Pioneering and headquartered in Lexington, MA. Valo also has offices in New York, NY. To learn more, visit www.valohealth.com.
