What are the responsibilities and job description for the Principal/Director, Medicinal Chemistry position at 5AM Ventures?
About Us
We are looking for dedicated professionals who thrive on tackling complex challenges and are committed to improving the lives of patients. If you value innovation, collaboration, and integrity, and are eager to contribute to advancing therapies for renal diseases, we encourage you to join our team. Based in the state-of-the-art Bakar Labs in Berkeley, CA, we are focused on pioneering medicines that make a meaningful impact.
About the Role
Renasant Bio is seeking a self-motivated medicinal chemistry leader capable of driving projects from hit generation through development candidate selection in a startup environment. The candidate should be a self-motivated and influential leader with a strong record of accomplishment in medicinal chemistry and CRO (Contract Research Organization) oversight.
This newly created role will report directly to our Senior Vice President, Chemistry.
\n- Apply the key principles of medicinal chemistry, literature precedent, and drug design to direct medicinal chemistry programs from hit finding to development candidate selection or series go/no go decisions
- Contribute to setting the overall drug discovery strategy and long-term pipeline development
- Present the rationale, strategy, and updates of the program chemistry efforts to scientists in other disciplines
- Drive design efforts; understand standard medicinal chemistry computational tools and can integrate the information from these tools into the design and evaluation of proposed targets
- Manage chemistry CROs; demonstrate good strategic thinking in allocating resources and prioritizing series
- Reduce ideas to practice quickly, optimize the design, make, test, analysis cycle
- Maintain an excellent record, including updating our data warehouse
- Contribute effectively to patent, report, and scientific publication writing
- PhD in organic chemistry or related fields with 7 years of experience in pharmaceutical / biotech setting.
- Team player with strong organizational and interpersonal skills. Experience functioning in a multidisciplinary, dynamic and highly matrixed environment
- Effectively collaborate with scientists/ teammates with diverse background
- Demonstrate a strong command of basic biology, pharmacology, ADME issues, and series SAR
- Strong track record of problem-solving skills and scientific creativity in synthetic and medicinal chemistry as evidenced by a significant publication record, filed patents and presentations.
- Excellent written and oral communication skills
- Prior experience successfully leading phenotypic projects from hit finding to development candidate selection would be a plus
- Prior experience in chemical biology, target deconvolutions strategies would a plus
We believe in building balanced teams. We are an equal opportunity employer. We do not discriminate in regard to race, color, religion, national origin, age, sex, sexual orientation, gender identity, marital status, ancestry, physical or mental disability, veteran status, or any other legally protected characteristics.
