What are the responsibilities and job description for the Computational Biologist position at Actalent?
Description
Support machine based learning for protein design models associated with various diseases
Develop and execute computational strategies for de novo design of vectors as AAVs, peptides, antibodies, to improve delivery of RNA therapeutics
Develop protein structure prediction and relevant machine learning models
Utilize structural biology methods to help further research efforts
Enhance capabilities for protein structure prediction and structural biology initiatives
Advanced programming and scripting skills in languages such as Python, R, and SQL, along with hands-on experience using modern deep learning frameworks like PyTorch, TensorFlow, scikit-learn, or JAX
Additional Skills & Qualifications
PhD in Structural Biology, Bioinformatics, Biochemistry, Protein Chemistry, or a related field, with over 3 years of relevant experience, ideally in the biotech or pharmaceutical industry.
Extensive experience with protein structure design applications, including Rosetta, AlphaFold, ESMFold, RFdiffusion, and ProteinMPNN is a must
Proficiency in developing machine learning models for proteins, including probabilistic learning and deep learning models such as Recurrent Neural Networks (RNNs), Graph Neural Networks (GNNs), Transformers, Protein Language Models, Natural Language Processing models, and Generative AI
GROMACS and AmberTools, as well as performing molecular docking studies with tools like AutoDock to analyze biomolecular interactions and predict binding affinities
Visualization and analytical tools like PyMOL for interpreting biomolecular structures
protein crystallography or cryo-EM techniques
Experience Level
Intermediate Level
Pay and Benefits
The pay range for this position is $50.00 - $55.00/hr.
Eligibility requirements apply to some benefits and may depend on your job classification and length of employment. Benefits are subject to change and may be subject to specific elections, plan, or program terms. If eligible, the benefits available for this temporary role may include the following:
• Medical, dental & vision
• Critical Illness, Accident, and Hospital
• 401(k) Retirement Plan – Pre-tax and Roth post-tax contributions available
• Life Insurance (Voluntary Life & AD&D for the employee and dependents)
• Short and long-term disability
• Health Spending Account (HSA)
• Transportation benefits
• Employee Assistance Program
• Time Off/Leave (PTO, Vacation or Sick Leave)
Workplace Type
This is a fully remote position.
Application Deadline
This position is anticipated to close on Mar 13, 2025.
About Actalent
Actalent is a global leader in engineering and sciences services and talent solutions. We help visionary companies advance their engineering and science initiatives through access to specialized experts who drive scale, innovation and speed to market. With a network of almost 30,000 consultants and more than 4,500 clients across the U.S., Canada, Asia and Europe, Actalent serves many of the Fortune 500.
Diversity, Equity & Inclusion
At Actalent, diversity and inclusion are a bridge towards the equity and success of our people. DE&I are embedded into our culture through:
- Hiring diverse talent
- Maintaining an inclusive environment through persistent self-reflection
- Building a culture of care, engagement, and recognition with clear outcomes
- Ensuring growth opportunities for our people
The company is an equal opportunity employer and will consider all applications without regard to race, sex, age, color, religion, national origin, veteran status, disability, sexual orientation, gender identity, genetic information or any characteristic protected by law.
If you would like to request a reasonable accommodation, such as the modification or adjustment of the job application process or interviewing process due to a disability, please email actalentaccommodation@actalentservices.com for other accommodation options.
Salary : $50 - $55
