Global Portfolio Manager - Pharma

Actylis is a global solutions provider with over 75 years of experience, specializing in streamlining the management of critical ingredients and raw materials for our business partners.

We offer both sourcing and manufacturing solutions tailored to meet diverse and evolving needs, ensuring a reliable, agile, and secure supply network. Our commitment to customization allows us to create flexible solutions, whether it’s a unique specification, custom packaging, or tailored logistics strategies.

With deep expertise in quality and regulatory compliance, sourcing and logistics management, analytical services, and R&D support, we reduce complexities and mitigate risks, empowering our partners to focus on growing their business.

In furtherance of that goal, Actylis is seeking new members of the team. This expansion, coupled with a comprehensive benefits package, and opportunities for challenge and growth, make Actylis the ideal place to work and thrive. We hope you’ll consider joining us!

Position Summary

The Global Portfolio Management function is a key strategic function within the company, responsible for overseeing and managing the global product portfolio team across multiple regions, and R&D pipelines. This leadership position will drive the alignment of portfolio strategies with business goals, ensuring optimized decisions and maximizing the return on innovation and commercial efforts.

This role is critical to the long-term sustainability and growth of our global pharmaceutical business. The Global Portfolio Manager must be a highly strategic, commercially driven leader capable of managing complex global portfolios while driving measurable business results. Only candidates with a demonstrated history of success in pharmaceutical portfolio management and market execution should apply.

Responsibilities will include:

Portfolio Strategy and Management – Pharma Focus

• Lead and execute a comprehensive global strategy for pharmaceutical direct materials, ensuring strategic alignment between market opportunities, customer needs, internal capabilities, and external sourcing partnerships.
• Develop & enforce robust portfolio management frameworks per industry segment, ensuring measurable alignment with corporate objectives, revenue targets, and market positioning.
• Oversee end-to-end product lifecycle management, from development & launch through post-market optimization, ensuring data-driven decision-making for maximizing portfolio value..
  
  

Make vs. Buy Analysis

• Conduct rigorous evaluations of internal manufacturing, R&D, and service capabilities, ensuring optimal utilization of proprietary resources and strategic prioritization of high-value products.
• Maintain real-time oversight of global supplier capabilities and align with Strategic Supplier Management to eliminate redundancies, optimize procurement, and drive cost efficiencies.
• Lead data-backed decision-making processes for sourcing and production, ensuring quantifiable business outcomes from Make vs. Buy assessments.
  
  

Financial Management

• Own financial performance of the portfolio, ensuring strict P&L accountability, margin optimization, and cost efficiency.
• Continuously track sales performance, cost structures, and profitability metrics, leveraging insights to drive revenue growth and improve EBITDA.
• Develop and enforce KPIs and ROI-driven portfolio investment strategies, ensuring capital allocation aligns with business objectives and delivers measurable returns.
  
  

Market and Competitor Analysis

• Maintain expert-level knowledge of global market trends, competitive landscapes, and technological advancements to inform proactive decision-making.
• Conduct granular market assessments, including competitor benchmarking, pricing analytics, and sales performance analysis to optimize market penetration strategies.
• Establish formalized market intelligence processes to ensure continuous assessment of customer demand, regulatory changes, and supplier capabilities, providing actionable insights to leadership.
  
  

Regulatory and Compliance

• Ensure absolute compliance with all global, regional, and local pharmaceutical regulations (GMP, ICHQ7, IPEC, ISO, REACH, FDA, USP, etc.), maintaining zero-tolerance for non-compliance risks.
• Serve as the primary liaison with Actylis regulatory leadership, ensuring product approval processes and maintaining full regulatory transparency across the portfolio.
• Support ongoing audits, risk assessments, and compliance initiatives.
  
  

Innovation and Product Development

• Drive strategic innovation initiatives, identifying unmet market needs and translating insights into actionable R&D roadmaps.
• Direct internal manufacturing and R&D teams, ensuring product development efforts are scientifically rigorous, commercially viable, and fully aligned with global strategy.
• Develop and implement structured processes for technology scouting, IP analysis, and commercialization, ensuring that innovation efforts lead to market-leading product offerings.
  
  

The salary range for the position of Global Portfolio Manager is $130,000 - $150,000 per year. Many factors go into determining employee pay within the range including prior experience, current skills, location/labor market, internal equity and other factors as permitted by law.

Required Experience & Knowledge

• Master’s degree or higher (MBA, MS, or PhD preferred) in Life Sciences, Business, Chemistry, Chemical Engineering, or a related field.
• 5 years of proven experience in pharmaceutical excipient, direct materials, or API portfolio management with a demonstrated track record of global product strategy execution.
• Industry Leadership: Expert knowledge of global Pharma direct materials (excipients, APIs, processing aids), customer manufacturing workflows, and best-in-class portfolio management practices.
• Strategic Execution: Ability to develop and implement high-impact portfolio strategies that drive double-digit revenue growth and ensure sustained market leadership.
• Regulatory Mastery: Deep expertise in GMP, ICHQ7, IPEC, ISO, REACH, FDA, USP, and other key regulatory frameworks.
• Commercial Acumen: Demonstrated ability to support and direct sales organizations, with a strong record of driving successful customer engagements and closing high-value deals.
• Technical & Financial Expertise:
• Strong technical acumen to engage with R&D, regulatory teams, and customers on complex product applications.
• Advanced proficiency in market research, business case development, financial modeling, and investment analysis to drive data-backed decision-making.
• Project & Stakeholder Management: Proven ability to manage cross-functional teams, influence stakeholders at all levels, and execute multiple high-priority initiatives under tight deadlines.
• Competitive Intelligence & Market Foresight: Strong command of market intelligence tools, predictive analytics, and industry benchmarking methodologies to stay ahead of competitors.
  
  

Work Environment

The work environment characteristics described here are representative of those an employee encounters while performing the essential functions of this job. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions. The noise level in the work environment is usually moderate.

Actylis is an Equal Opportunity Employer. Actylis US does not discriminate on the basis of race, religion, color, sex, gender identity or expression, sexual orientation, age, non-disqualifying physical or mental disability, national origin, veteran status or any other basis covered by appropriate law. All employment is decided based on qualifications, merit, and business need.