Senior Research Associate In Vivo

AcuraStem is a patient-based biotechnology company pioneering the development of treatments for amyotrophic lateral sclerosis (ALS), Frontotemporal dementia (FTD), and additional neurodegenerative diseases .   We are a purpose-driven company on a mission to get our promising treatments into patients' hands as quickly as possible.

AcuraStem’s best-in-class disease modeling platform, iNeuroRx®, is the gold standard for discovering novel, effective, and broadly-acting treatments. The AcuraStem team’s extensive expertise in ASO technology is accelerating the advancement of treatments to the clinic.

At AcuraStem, we know that empowered and supported colleagues strengthen our commitment and significantly enhance our collective mission. We are committed to scientific excellence, impactful results, persistence, attention to detail, teamwork, sound decision-making, and continuous learning.

We are seeking a highly skilled and well-organized Senior Research Associate to contribute to our research programs and drive scientific progress.  The Senior Research Associate will work closely with AcuraStem scientists, executing and refining experimental protocols with precision. The ideal candidate will have experience handling rodents and be adept at following detailed protocols meticulously while also demonstrating the ability to propose improvements when necessary.

Responsibilities :

• Design, execute and manage in vivo experiments assessing the efficacy and safety of test agents in various rodent models.
• Perform a range of in vivo techniques, including rodent handling, various routes of compound administration (IV, ICV, IT), tissue collection, and behavioral assessments.
• Manage mouse colonies and perform breeding, weaning, and genotyping.
• Conduct various laboratory assays, including immunohistochemistry, microscopy, and biochemistry / molecular biology.
• Analyze and interpret experimental data, and prepare scientific documents including study reports, protocols, and other related materials for presentations, regulatory submissions and publications.
• Maintain accurate records of experimental data and protocols in accordance with AcuraStem guidelines.
• Collaborate effectively with internal / external resources to schedule and execute tasks independently with minimal training / guidance from manager.
• Independently conducts multiple complex experiments and provides technical guidance and problem solving related to methods, procedures and processes, and obtain optimum solutions.
• Provide technical guidance and problem-solving related to methods, procedures, and processes to the work group.
• Mentor and train junior lab m embers, promoting a positive and collaborative research environment.

Desired Skills and Experience :

Additional Information :

50%) to various AcuraStem laboratory sites in Los Angeles.

Compensation / Benefits :

Diversity, Inclusion, and Recruitment Practices at AcuraStem :

Qualified candidates, please submit your CV / resume to jobs@acurastem.com

Salary : $82,000 - $115,000