What are the responsibilities and job description for the Process Development Engineer 2/3 position at Adicet Bio?
Process Development Engineer 2/3
Responsibilities:
- Lead and execute experiments to support process development, process scale-up, and technology transfer of ɣδ CAR T- cell products
- Execute cell culture-based experiments utilizing novel technologies to improve and scaling-up processes such as novel isolation methods, new bioreactors, and new reagents
- Create improvements to the platform process for activation, transduction, and expansion unit operations
- Perform multi-color flow cytometry acquisition and analysis
- Tracking and ordering requisite consumables for PD and MS&T teams
- Accurately compile data in electronic notebook entries and aggregate data files
Qualifications:
- BS/MS in Biochemical Engineering, Chemical Engineering, Science or Biotechnology.
- BS with 3-5 years or MS with 2 years’ experience in industry setting
- A strong background in cell therapy or CAR T products required
- Experience in aseptic technique, cell culture, and retroviral or lentiviral transductions
- Experience with scale-up cell processing equipment such as closed system bioreactors, LOVO, Sefia, CliniMACS
- Familiar with flow cytometry for T cells and FlowJo
- Experience with Microsoft Office suite, JMP, Prism, Benchling (or other electronic lab notebook software)
- Experience with GMP processing and/or tech transfer related activities a plus
- Experience with analysis and reporting results, and interpretation of data.
- Possesses good verbal and written communication skills
- Ability to operate in a fast paced, dynamic industrial environment
