What are the responsibilities and job description for the Technical Development Scientist II position at Aequor?
Job Title : Technical Development Scientist
Location : South San Francisco, CA
Duration : Until 10/14/2025
Job Knowledge & Scope
Location : South San Francisco, CA
Duration : Until 10/14/2025
Job Knowledge & Scope
- RMG, in the Cell Culture and Bioprocess Operations department, is responsible for providing support to pre-Early Stage Research to Early Development projects with high-throughput protein production from mammalian transient cultures.
- We are looking for a motivated candidate with cell culture and sterile technique experience to join our team to enable protein production and help advance our portfolio.
- Perform transient transfections in CHO and HEK293 cells in scales 1mL to 25L to support pipeline productions adhering to established protocols
- Maintain seed train cell cultures in bioreactors and shake flasks
- Operate liquid handlers - Tecan and Hamilton for automated processes
- Operate wave bag reactors for productions and cell maintenance
- Maintain and troubleshoot key cell culture instruments such as Vi-Cell, Nova Flex2, Nova Flex, Cedex and bioreactors
- Participate in troubleshooting production or platform processes
- Participate in lab management and data management.
- Contribute to improving existing cell culture platforms and developing new platforms to deliver diverse protein and cellular reagents to enable a large number of research programs.
- The candidate must be highly self-motivated, organized, detail oriented and responsive to feedback.
- The candidate is expected to precisely follow written procedures, practice sterile technique, demonstrate accurate documentation skills, and report deviations in a timely manner.
- They should be able to work independently within guidelines and policies, with minimal guidance.
- PhD (with 0-2yrs relevant experience) in Biotechnology, Chemistry, Biochemistry or related fields
- Suspension adapted mammalian cell culture (CHO and/or HEK293)
- Excellent written and verbal communication skills, and have strong collaborative skills.
- State-of-the-art transient and stable protein expression experience
- Relevant bioreactor experience
- Hands-on experience with automation and liquid handlers like Tecan Freedom Evo and Hamilton Microlab Star
- Knowledge of cell biology, cell engineering, molecular biology, recombinant protein purification and protein characterization is preferred
