Demo

Director/Senior Director, Program Management

Aera Therapeutics
Cambridge, MA Full Time
POSTED ON 2/25/2025
AVAILABLE BEFORE 3/23/2025

ABOUT US

Aera Therapeutics was founded with a vision to unlock the potential of genetic medicines across a broad range of modalities and therapeutic areas.


Our novel protein nanoparticle (PNP) delivery platform is based on endogenous human proteins, leveraging the discovery of human proteins derived from retroelements that self-assemble to form capsid-like structures and which can package and transfer nucleic acid cargo. This platform combines the benefits of an endogenous, fully synthetic self-assembling system with the engineerability of a protein-based system and has the potential to enable various genetic medicine modalities.


With a world-renowned scientific founder and a distinguished Board of Directors, Aera has raised $193 million led by Arch Venture Partners, GV, and Lux Capital.


How will your role make an impact at Aera Therapeutics?

Reporting to the SVP, Operations, you will help drive the strategic direction and execution of our pipeline programs, ensuring that our therapeutic candidates advance through development in a timely and efficient manner. You are a hands-on, active leader that has experience leading cross functional teams and is committed to delivering results that align with corporate goals.

This is an on-site role based in our Cambridge, MA headquarters.


You will:

  • Oversee the planning, execution and monitoring of research and development programs.
  • Manage cross functional teams including research, clinical, regulatory, safety and manufacturing to ensure critical activities are fully integrated into the development plan
  • Achieve organizational agreement and seamless execution by working cross functionally within Aera and with our selected CROs. Develop strong working relationships with necessary external partners.
  • Define critical path, at-risk activities, and inter-dependencies. Anticipate bottlenecks, and clear barriers to progress program.
  • Lead program team meetings. Facilitate clear presentation of action items and deliverables, calling for and driving action if required
  • Support active portfolio management and decision making (budget, resources, stage-gates where relevant); monitor progress of portfolio/program strategy, goals, and metrics


Qualifications:

  • Bachelor's degree in science or related field; an Advanced degree preferred
  • Minimum 8-10 years of relevant biotech or pharmaceutical industry experience with 5-7 years in program management with genetic medicines.
  • Experience managing complex drug development programs from early stage research through clinical.
  • Strong leadership and team management abilities with experience leading cross functional teams.
  • Experience with regulatory requirements and drug development process.
  • Strategic and engaged leader with a focus on results and problem-solving. Handle complexity and ambiguity and be able to prioritize effectively
  • Excellent written and verbal communication. Can clearly and concisely communicate complex program information in both formal and informal settings, both verbally and in presentation media
  • Experience helping teams establish plans, identify challenges and solutions, and driving for decisions
  • Experience managing programs from preclinicial through IND and beyond.
  • Work onsite at least 3 days per week.


Benefits

  • Healthcare
  • 401K
  • Flexible PTO
  • Commuting subsidy
  • Parental leave


Aera Therapeutics is committed to providing equal employment opportunities by recruiting, hiring, training and promoting applicants and employees without regard to race, color, religion, creed, national origin, sex, age, ancestry, sexual orientation, genetics, pregnancy, marital status, familial status, victim of domestic violence status, gender identity/expression, disability, handicap, military obligations, veteran status or any other category protected by federal, state or local laws.


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