What are the responsibilities and job description for the PNP Senior Scientist, Delivery Technologies position at Aera Therapeutics?
ABOUT US
Aera Therapeutics was founded with a vision to unlock the potential of genetic medicines across a broad range of modalities and therapeutic areas.
Our novel protein nanoparticle (PNP) delivery platform is based on endogenous human proteins, leveraging the discovery of human proteins derived from retroelements that self-assemble to form capsid-like structures and which can package and transfer nucleic acid cargo. This platform combines the benefits of an endogenous, fully synthetic self-assembling system with the engineerability of a protein-based system and has the potential to enable various genetic medicine modalities.
With a world-renowned scientific founder and a distinguished Board of Directors, Aera has raised $193 million led by Arch Venture Partners, GV, and Lux Capital.
How will your role make an impact at Aera Therapeutics? Aera Therapeutics is looking for an experienced Senior Scientist to join the Delivery Technologies team focused on developing Protein Nanoparticles (PNPs). You will report into our Associate Director, Delivery Technologies and your role will involve the design, formulation, and characterization of PNPs with desired functionalities in downstream applications. You will be an individual contributor in this role and will be onsite five days per week in our Cambridge headquarters.
You will:
- Design proteins for PNP formation and functionality in vitro
- Work with cross-functional teams to evaluate PNP functionalities in vivo
- Develop PNP assembly protocols for small and medium scale formulations
- Propose new scientific directions and provide creative solutions to scientific challenges
- Record and maintain all relevant data in the electronic laboratory notebook system
- Manage and train junior Scientists and Research Associates
Qualifications:
- Bachelor’s degree with 10 years’ experience, Master’s degree with 8 years of experience, or PhD with 5 years’ experience in Biochemistry, Virology, Structural Biology, or an Engineering discipline
- Knowledge of protein biochemistry and protein design required
- Demonstrated application of protein design and engineering principles to virus capsids, virus-like particles, or nanoparticles required
- Proficiency in nanoparticle characterization techniques such as DLS and EM
- Familiarity with protein bioconjugation techniques
- Commitment to our Core Values: Respect, Integrity, Excellence, Impact
Benefits:
- Healthcare
- 401K
- Flexible PTO
- Commuting subsidy
- Parental leave
Aera Therapeutics is committed to providing equal employment opportunities by recruiting, hiring, training and promoting applicants and employees without regard to race, color, religion, creed, national origin, sex, age, ancestry, sexual orientation, genetics, pregnancy, marital status, familial status, victim of domestic violence status, gender identity/expression, disability, handicap, military obligations, veteran status or any other category protected by federal, state or local laws.
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