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Research Associate, Preclinical Analytics (RA II - SRA)

Affinia Therapeutics
Watertown, MA Full Time
POSTED ON 2/10/2025
AVAILABLE BEFORE 5/4/2025

Affinia Therapeutics is biotech company developing transformative gene therapies for devastating cardiovascular and neurological diseases. We are backed by a strong syndicate of life science investors and have ambitious plans to have a dramatic impact on the lives of patients around the world. The pace of work is dynamic, fast and fun.

We are looking for a curious, organized and self-motivated individual to join our team at Affinia. Team members work together across functions for a common purpose. This is an excellent opportunity to gain experience and develop in a dynamic, next-generation gene therapy environment.

We offer competitive salary and benefits with the ability to make a difference.

Position Summary

Affinia Therapeutics is seeking an experienced Research Associate (job level will commensurate with experience) to join our Preclinical Analytics laboratory team. You will be part of a group dedicated to the advancing of gene therapies based on vectors derived from our unique AAV platform. You will actively contribute to the development and execution of analytical assays supporting studies conducted by the translational science team at Affinia. You will work to establish methods and analyze samples to meet timelines for our internal development programs. You will contribute to the evaluation of new analytical technologies, the development of more efficient laboratory workflows as well as maintaining a culture of quality and excellence.

This is a lab-based role (5 days a week in the office) located at our state-of-the-art facility in Waltham, MA.

Primary Responsibilities

  • Contribute to the development of analytical methods to support preclinical studies using platforms such as ddPCR, qPCR, Western Blotting / Jess automated Western Blot, and ELISA
  • Execute routine sample testing to support preclinical studies
  • Document laboratory experiments, review peer data, organize experimental results for further analysis
  • Work cross-functionally with other laboratory groups for timely generation of data, and to assist with transfer of qualified assay methods to cross-functional colleagues and CRO partners as needed
  • Assist in the implementation of new laboratory workflows and continuous improvement efforts

Minimum Qualifications

  • Requires a bachelor's degree and 2-5 years of related experience, or an advanced degree with 1-4 years of related experience in an industry setting
  • Excellent written and oral communications skills, including experience writing laboratory SOPs, protocols, and reports
  • Experience performing Western Blotting / Jess automated Western Blot and dd-PCR methods
  • Ability to thrive in a fast-paced environment flexibly and collaboratively
  • Operate daily with Integrity, Teamwork, and Passion
  • Preferred Qualifications

  • Experience in analysis of preclinical samples for biomarker, biodistribution and safety parameters
  • Previous animal tissue processing experience
  • Experience with IND-enabling studies
  • Familiarity with GXP procedures and regulatory guidelines
  • EEO Statement : Affinia Therapeutics is proud to be an equal opportunity workplace. We are committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status. If you have a disability or special need that requires accommodation, please let us know.

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