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Associate Scientist\Scientist, Chemical Development and Manufacturing

Agios Pharmaceuticals Inc
Agios Pharmaceuticals HQ, MA Full Time
POSTED ON 2/16/2025
AVAILABLE BEFORE 4/14/2025

Associate Scientist/Scientist, Chemical Development and Manufacturing

Who we are:

Agios is a biopharmaceutical company that is fueled by connections. We thrive in a supportive, fun, and flexible environment full of people empowered to bring their whole selves to work. We care deeply about our work, each other, and the patients who count on us. Our teams cultivate strong bonds with patient communities, healthcare professionals, partners and colleagues, which helps us discover, develop and deliver therapies for rare disease – and make a bigger difference in their lives. In the U.S., Agios markets a first-in-class pyruvate kinase (PK) activator for the treatment of hemolytic anemia in adults with PK deficiency. Building on the company’s leadership in the field of cellular metabolism, Agios is advancing a robust clinical pipeline of investigational medicines with active and planned programs in alpha- and beta-thalassemia, sickle cell disease, pediatric PK deficiency and MDS-associated anemia.  

The impact you will make:

Agios Pharmaceuticals is searching for a dynamic Associate Scientist / Scientist to join our growing Process Chemistry team. We want someone who cares about this important work, and who’s driven to connect to our mission of helping these patient communities. The chemist will be emersed into all aspects of small molecule development from process design to cGMP manufacturing. The role will solve technical challenges and develop sustainable processes to provide unhindered drug supply to patients. The chemist will significantly grow in this role gaining experience in data driven process development, CDMO management, production, CMC, and regulatory submissions.

What you will do:

  • Solve technical issues relating to external drug substance manufacturing by providing hands-on experimentation and development.

  • Support drug substance process design, optimization, scale-up, intensification, and technology transfer

  • Assist in authoring internal technical reports based on in-house laboratory research and provide critical review of similar reports generated at external CMO/CROs

What you bring:

  • MS or PhD in organic chemistry or chemical engineering with 2-5 years (MS) or 0-4 years (PhD) of industry experience

  • Must have knowledge and understanding of organic chemistry including expert hands-on experience.

  • Ability to navigate and be successful in a fast-paced, highly-matrixed work environment

  • Effective verbal and written communication skills

Work Location:

Location Specific – Onsite: This role requires the majority of work to be completed onsite at our Cambridge Headquarters. While it is expected that this role will be onsite a minimum of 4 days a week, Agios values flexibility, and flexible schedules around onsite work are available. Regular conversations with manager are encouraged to ensure alignment on in-person presence/expectations. Employees in this role are expected to live within a commutable distance to the office.   

What we will give you:

Deliberate Development. Your professional growth is one of our top priorities.

Flexibility. We’re all about individual needs. We embrace different perspectives, work styles, health and wellness approaches, care of families and productivity. When you’re at your best, we’re at our best.

Premium benefits package. We invest in the health, well-being and security of our people with a premium benefits package that is well-rounded and flexible to help meet the varied personal and professional needs of every member of our team.

Competitive performance-based compensation. This includes both short- and long-term incentives that are connected to our business strategy.

Psychological safety.  We support an environment of fearlessness. We want you to share your ideas, speak candidly and take data-informed risks to help push the boundaries.

Commitment to diversity. We strive to foster a welcoming workplace where everyone can thrive. We’re continuously looking to improve the inclusivity of our workforce.

Commitment to community. We’re an active participant in the communities that surround us – the communities where we live, and the community of people and their loved ones in need of better treatment options for conditions that are often overlooked.

Interested in learning more about what makes our culture unique? Visit the Inside Agios section of our website

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