Research Associate II – In Vivo Pharmacology - Temporary

Our mission is to develop therapies that empower the immune system to combat neurodegeneration and our team is focused on developing treatments for some of the most challenging diseases facing our society. By harnessing advancements in genetics, immunology and neuroscience, we are pioneering the development of potential therapies to counteract the devastating progression of neurodegeneration. We are supported in this mission by experienced and accomplished scientists and clinicians, a novel portfolio of programs, leading healthcare investors, and pharma company partners, who share in our commitment to bettering the lives of patients and realizing a world where we make brain disorders history.

Research Associate II – In Vivo Pharmacology will be responsible for conducting in vivo studies to evaluate potential therapeutics for neurodegenerative diseases. This role involves handling and dosing rodents, collecting samples for downstream biochemical assessments, assisting in animal disease model development, and maintaining accurate records to support PK/PD, efficacy, safety, POC, MOA in vivo studies.

• Perform in vivo pharmacology studies in rodent models of neurodegenerative diseases, including dosing (IV, IP, SC, PO, ICV) and tissue collection.
• Collect and process biological samples (blood, CSF, brain, and other organs) for downstream analysis.
• Assist in the development and optimization of disease models, including Parkinson’s and Alzheimer’s disease, POC, MOA models.
• Maintain accurate records of experiments, protocols, and data in electronic lab notebooks (ELN).
• Collaborate daily with cross-functional teams, including Biology, ADPE, and Preclinical groups.
• Ensure compliance with IACUC protocols and maintain high standards of animal welfare.

• BS/MS in Neuroscience, Immunology, Biology, or a related field with 2 years of in vivo research experience (industry experience preferred).
• Hands-on experience with rodent handling, dosing techniques, in-life and terminal blood collection, and necropsy.
• Familiarity with lymph node harvesting and CSF collection is a plus.
• Familiarity with stereotaxic surgery and neuroanatomy is a plus.
• Proficient in Word, Excel, PowerPoint, and GraphPad Prism.
• Excellent organizational and communication skills.
• Strong attention to detail.
• Highly adaptable and capable of adjusting to shifting priorities.
• Able to work in a fast-paced and highly collaborative environment.

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At Alector, our vision is bold, people are our priority, and our values are at the core of everything we do. Our dynamic and flexible environment encourages our teams to experiment, take ownership of decisions, and question convention to solve complex problems. We value shared wins, perseverance, and a growth mindset, which drives us forward, together.  

Among the things you'll discover at Alector from your very first day are our committed and driven colleagues, a bold company vision, and new, modern offices designed to inspire innovation and collaboration in South San Francisco, right at the heart of Biotech Bay. Our benefits are thoughtfully designed around Alectorians and their loved ones and include flexible hybrid work options, competitive compensation, and comprehensive and unique benefits that enhance your health and well-being. Come join us! 

We believe that hard-working teams include people from a wide variety of backgrounds and experiences who can challenge each other’s assumptions with fresh perspectives and bring creative ideas to the table. We are committed to building an open, diverse, and inclusive environment for all employees. We do not discriminate on the basis of race, religion, color, national origin, sex, gender, sexual orientation, age, marital status, veteran status, or disability status, or any other characteristics protected under applicable federal, state, or local laws.  

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, perform essential job functions, and receive other benefits and privileges of employment. Please contact us to request accommodation. 

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Salary : $40 - $50