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Senior Director Nonclinical Science

Alector
South San Francisco, CA Full Time
POSTED ON 2/9/2025
AVAILABLE BEFORE 5/7/2025

Our mission is to develop therapies that empower the immune system to combat neurodegeneration and our team is focused on developing treatments for some of the most challenging diseases facing our society. By harnessing advancements in genetics, immunology and neuroscience, we are pioneering the development of potential therapies to counteract the devastating progression of neurodegeneration. We are supported in this mission by experienced and accomplished scientists and clinicians, a novel portfolio of programs, leading healthcare investors, and pharma company partners, who share in our commitment to bettering the lives of patients and realizing a world where we make brain disorders history.The Senior Director of Nonclinical Science will provide scientific leadership and strategic oversight in Nonclinical evaluations of Alector pipeline programs. The successful candidate will work in close partnership with Research and Development teams to facilitate seamless execution.

During your first year, you will :

  • Lead and supervise the Toxicology and BioAnalytical teams
  • Provide strategic guidance on Nonclinical evaluations of pipeline programs. Design, execute Nonclinical studies and interpret study results together with the Toxicology team to advance programs.
  • Oversee the preparation, review and approval of Nonclinical Regulatory documents and collaborate with the Toxicology and Regulatory teams for interactions with Health Authorities
  • Supervise the BioAnalytical team for PK / PD / ADA assay development to support clinical programs, nonclinical programs and early stage research programs.
  • Manage Nonclinical budget, FTE and other internal and external resources effectively to ensure program timelines, goals and priorities are met
  • Establish and maintain close partnership with key collaborators across the organization to drive programs forward, contribute to a team culture that promotes ownership, collabration and perseverance.

We would love to hear from you if :

  • PhD in Toxicology or related scientific field, with at least 15 years of post-training experience in academia, biotech or pharma. Industry experience in drug discovery and development required
  • Demonstrated leadership and expertise in non-clinical safety and a broad understanding of toxicology / pathology, bioanalytical, ADME, regulatory and clinical pharmacology.
  • Proven ability to lead and collaborate on multi-function project teams, providing scientific and strategic direction to advance drug candidates from preclinical stage into clinical trials.
  • Desire to work in a fast-paced environment with can-do attitude.
  • Exceptional critical thinking and decision making skills
  • Exceptional oral presentation and written communication skills
  • 262,080 - $283,466 a yearBase salary ranges will be determined by the candidate’s level, qualifications, skill set, and experience.

    Salary : $262,080 - $283,466

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    Job openings at Alector

    Alector
    Hired Organization Address South San Francisco, CA Full Time
    Our mission is to develop therapies that empower the immune system to combat neurodegeneration and our team is focused o...
    Alector
    Hired Organization Address South San Francisco, CA Full Time
    Our mission is to develop therapies that empower the immune system to combat neurodegeneration and our team is focused o...

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