Demo

Analytical Scientist

Alexander Rose International
San Francisco, CA Full Time
POSTED ON 4/3/2025
AVAILABLE BEFORE 5/2/2025

πŸ”¬ Analytical Scientist

πŸ“ San Francisco, CA (On-site)

πŸ§ͺ Full-Time | Oncology Drug Discovery | ADCs


Alexander Rose International has partnered with a clinical-stage biotech developing transformative therapies for immune-mediated and rare diseases.


We are seeking a hands-on Bioanalytical/ analytical Scientist to join a lean and dynamic research team in San Francisco. This role will support the development of antibody-drug conjugates (ADCs) and other novel oncology therapeutics β€” with a strong focus on method development, compound characterization, and IND-enabling studies.


πŸš€ What You'll Do

  • Perform HPLC (RP/IEX/SEC), LC/MS, CE-SDS, cIEF, and spectrophotometry-based analysis of small molecules and biologics
  • Develop and optimize new bioanalytical methods in support of a versatile drug pipeline
  • Collaborate with CROs and internal teams to advance IND-enabling studies
  • Prepare and analyze samples, maintain accurate lab records (ELN), and write reports and SOPs
  • Troubleshoot instrumentation (AB Sciex, Thermo, Agilent, Bruker, etc.) and support lab operations


πŸ‘€ Requirements

  • MS in Analytical Chemistry, Biophysics, or Biochemistry with 4 years of industry experience, or PhD with 0–2 years
  • Proven experience with LC/MS, HPLC, and CE techniques in a pharma/biotech setting
  • Comfortable working in a hands-on, startup-like environment as all scientists work at the bench
  • Familiarity with ADC characterization, small molecule/biologic workflows, and CRO partnerships is highly desired
  • Detail-oriented with strong critical thinking and excellent documentation skills


⭐ Additional Selling Points

  • Experience with antibody-drug conjugates (ADCs) or linker-payload systems
  • Knowledge of proteomics and bioinformatics tools
  • Exposure to early-stage biotech and IND-filing processes


βœ… Job Functions:

  • Research
  • Quality Assurance
  • Science


πŸ“© Interested? Apply now or reach out directly for a confidential conversation.

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