Demo

Sr. Scientist, Formulation Development

Alkermes
Watertown, MA Full Time
POSTED ON 2/5/2025
AVAILABLE BEFORE 5/4/2025

Job Description

Position Description

Join us in this exciting role as Sr. Scientist where you'll provide great impact in leading technical innovation while also designing and executing lab experiments for small molecule formulation development.

Responsibilities

  • Provide technical leadership in designing and executing lab-based experiments to develop small molecule formulations across various stages.
  • Support strategic planning and meet project deliverables within timelines, incorporating both immediate and long-term goals.
  • Collaborate effectively within a team-based environment, fostering diversity, inclusion, and belonging.
  • Maintain and enhance scientific / technical knowledge, champion ideas for new projects, and serve as a role model within the scientific / technical community.
  • Utilize creative scientific skills and demonstrate mastery of materials understanding and drug product unit operations.
  • Emphasize the importance of collaboration for project success.

Qualifications

  • Deep and thorough understanding of chemical and material science, engineering, and development of pharmaceutical dosage forms with a focus on how physicochemical properties impact dosage form development and product quality.
  • Proficiency in development / lab-scale production equipment such as tableting, granulation, blending, milling, spray drying, coating, drying.
  • Demonstrated a track record of solving complex technical problems and showcasing leadership in a technical capacity.
  • Experience developing small molecule formulations for clinical studies.
  • Excellent communication, organization, and planning skills, along with a high level of technical aptitude and creativity.
  • Solid knowledge of cGMPs and applicable regulatory guidance.
  • Proven ability to apply scientific principles to design, execute, and interpret experiments.
  • Ability to interact and collaborate within a diverse and interdisciplinary team environment on creative problem-solving, fostering diversity, inclusion, and belonging.
  • Skilled in analytical methods such as PXRD, TGA, DSC, HPLC, GC, GC / MS, NMR, FTIR, and UV.
  • Proficiency in standard computer applications (MS suite, ChemDraw, SciFinder, Statistical Design, ELN's).
  • Degree in chemical engineering, pharmaceutical science, materials science, or related physical science with a PhD and 3 years, or an MS with 10 years, or a BS with 15 years of experience in pharmaceutical development.
  • Experience with PAT / Chemometrics, Continuous Manufacturing, and / or QbD is preferred.
  • LI-MB1

    About Us

    Why join Team Alkermes?

    Alkermes applies its deep neuroscience expertise to develop medicines designed to help people living with complex and difficult-to-treat psychiatric and neurological disorders. A fully-integrated, global biopharmaceutical company, headquartered in Ireland with U.S. locations in Massachusetts and Ohio, we are committed to pursuing great science, driven by deep compassion to make a real impact in the lives of patients. Alkermes has a portfolio of proprietary commercial products for the treatment of alcohol dependence, opioid dependence, schizophrenia and bipolar I disorder, and a pipeline of clinical and preclinical candidates in development for various neurological disorders, including narcolepsy.

    Beyond our important mission of developing medicines to address unmet patient needs, we actively seek to foster a culture of diversity, inclusion and belonging throughout our business. We strive to ensure that all voices are respected and valued, recognizing that our diversity of thought, background and perspective makes us stronger. We are proud to have been recognized as an employer of choice by many national organizations, including being certified as a Great Place to Work in the U.S. in 2024, honored as a Healthiest Employer in both Ohio and Massachusetts in 2023, a Best Place for Working Parents in 2023, and to have received the Bell Seal at the Platinum level for Workplace Mental Health by Mental Health America for three consecutive years (2021-2023).

    Alkermes, Inc. is an equal employment opportunity employer and does not discriminate against any qualified applicant or employee because of race, creed, color, age, national origin, ancestry, religion, gender, sexual orientation, gender expression and identity, disability, genetic information, veteran status, military status, application for military service or any other characteristic protected by local, state or federal law. Alkermes also complies with all work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Alkermes is an E-Verify employer.

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