Job Description
We seek an experienced and creative medicinal chemist with a proven track record of success in drug discovery. Candidates should be motivated to work in an intensely collaborative, multidisciplinary, team-based setting. The role will entail coordinating a medicinal chemistry team with internal and external experimental capabilities, as well as proactively interfacing with diverse teams working on automated experimentation, AI-driven molecular generation, property predictions, and bioassay data generation.
KEY RESPONSIBILITIES
- Lead a group of medicinal chemists and drive molecular discovery efforts to deliver development and clinical candidates
- Devise strategies to identify lead molecules and optimize them for potency, selectivity, and ADME properties using multivariant SAR analysis and hypothesis driven design principles
- Work closely with molecular and cellular biology, pharmacology, computational chemistry,
ADME, and other key functions
Act as liaison between Entos, CROs, and other external partnersInfluence the prospective use of computational methods and leverage automated synthesisand high-throughput experimentation capabilities
Work closely with AI / ML teams to develop and implement relevant predictive models to aidin the design of new molecules
Communicate project updates clearly and effectively to the broader team and keystakeholders
Work as a senior member of the Chemistry research group and foster a culture of scientificexcellence, innovation, and teamwork
PREFERRED QUALIFICATIONS
A Ph.D. / Postdoc in organic chemistry with 8 or more years of experience in Pharma / Bio-tech drug discoveryExpert in modern synthetic organic chemistry approaches and principles demonstrated through publications in journals and patentsAbility to integrate multiple R&D disciplines into a successful strategic project planExperience in leading projects and driving programs through the preclinical developmentprocess
Experience working with computational chemists as part of project team in design of drug targets is requiredStrong interpersonal, communication, time management, and leadership skillsExperience mentoring or leading junior chemistsCreative problem solving and management of relationships with several stakeholders withinand beyond the company
Requirements
PREFERRED QUALIFICATIONS
A Ph.D. / Postdoc in organic chemistry with 8 or more years of experience in Pharma / Bio-tech drug discoveryExpert in modern synthetic organic chemistry approaches and principles demonstrated through publications in journals and patentsAbility to integrate multiple R&D disciplines into a successful strategic project planExperience in leading projects and driving programs through the preclinical developmentprocess
Experience working with computational chemists as part of project team in design of drug targets is requiredStrong interpersonal, communication, time management, and leadership skillsExperience mentoring or leading junior chemistsCreative problem solving and management of relationships with several stakeholders withinand beyond the company
Benefits
Dental, Medical, Vision and 401K
