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Scientist, Cell Biology

ALS TDI
Watertown, MA Full Time
POSTED ON 2/22/2025
AVAILABLE BEFORE 2/20/2030

About Us: The ALS Therapy Development Institute (ALS TDI) is a leading non-profit biotechnology company dedicated to discovering and advancing effective treatments for amyotrophic lateral sclerosis (ALS). At ALS TDI, we are driven by our mission to find therapies that can make a real difference for patients living with ALS.


Position Overview: We are seeking a dynamic and highly motivated Scientist to join our Cell Biology research team. In this role, you will contribute to the development of advanced cell-based models of ALS and play a key role in chemical and genetic screening initiatives for drug target identification and therapeutic discovery. This is an exciting opportunity to work in a collaborative, mission-driven environment and make a tangible impact on ALS research.


Key Responsibilities:

  • Develop innovative induced pluripotent stem cell (iPSC)-based models of ALS using patient-derived fibroblasts and genome-edited cell lines.
  • Perform neural differentiations to generate cellular models for phenotype discovery.
  • Design, execute, and manage experiments with a high level of scientific rigor.
  • Analyze experimental data and present findings to the Cell Biology team and at company-wide meetings.
  • Stay informed of the latest scientific advancements and proactively share new ideas, methodologies, and insights with colleagues.

Minimum Qualifications:

  • Education: MS/MA or Ph.D. in Molecular and Cell Biology or a related field.
  • Experience: Proven experience with mammalian cell culture and general molecular and cellular biology techniques.
  • Preferred Skills: Background in neurobiology, stem cell biology, cellular immunology, genome editing, cell-based assay development, laboratory automation, or high-content cell analysis.
  • Attributes: Strong organizational and communication skills, attention to detail, and the ability to work both independently and collaboratively on multiple projects.

Why Join Us?

  • Be part of a passionate and innovative team dedicated to making a difference in the lives of ALS patients.
  • Collaborate in a cutting-edge research environment with opportunities for professional growth and development.
  • Contribute to impactful scientific discoveries that bring us closer to effective ALS treatments.

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