What are the responsibilities and job description for the Principal Scientist - Bioanalytical Science position at Amgen SA?
Join Amgen’s Mission of Serving Patients At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do.Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas –Oncology, Inflammation, General Medicine, and Rare Disease– we reach millions of patients each year. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives.Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.Principal Scientist - Bioanalytical ScienceWhat you will do Let’s do this. Let’s change the world. The Translational Safety and Bioanalytical Sciences (TS&BA) organization is seeking to fill a Principal Scientist position in our LC-MS / MS Bioanalytical Sciences group at the Amgen Thousand Oaks site in California. In this role, you will implement robust LC-MS / MS bioanalytical methods to support a broad range of therapeutic agents, including small molecules, oligonucleotides, proteins, and other complex molecular entities. Given the scope of projects, the role will involve multidisciplinary interactions with scientists across research and development at Amgen. The position is lab based, and has significant emphasis on data management / fidelity, report generation, project-based leadership, and communication across multiple teams.Key Responsibilities : Ensure bioanalytical data meets regulatory expectations for global submissions by maintaining accurate records and staying current with industry guidelines.Develop and implement LC-MS / MS bioanalytical methods with quick turnaround times.Conduct small and large molecule bioanalysis in non-clinical and clinical samples from various matrices (plasma, urine, CSF, tissues).Perform biological sample extraction using SPE, protein crash, and / or affinity capture methodologies.Author study reports, standard operating procedures, analytical methods, memos, and other regulatory-compliant documents.Communicate bioanalytical data to key discovery and development teams, contribute to scientific publications, and present at professional meetings.What we expect of you We are all different, yet we all use our unique contributions to serve patients. The dynamic professional we seek is a highly collaborative, motivated scientist with these qualifications.Basic Qualifications : Doctorate degree PhD OR PharmD OR MD [and relevant post-doc where applicable] and 2 years of relevant scientific experienceOr Master’s degree and 5 years of relevant scientific experienceOr Bachelor’s degree and 7 years of relevant scientific experiencePreferred Qualifications : Ph.D. in a relevant scientific disciplinePrior GLP and GCP experiencePrior experience in bioanalytical (regulated) assay execution and transfer to CROsStrong technical expertise in quantitative mass spectrometry particularly on triple quadrupole (QQQ) platformsBroad experience with an array of analytical technologies that can accelerate bioanalysis inclusive of automation, low flow chromatographic approaches, high resolution mass spectrometry, and / or microsamplingDemonstrated ability to resolve scientific challenges efficiently and prioritize effectivelyDemonstrated scientific breadth and subject matter expertiseSupervisory and mentoring experience in a lab-based settingAbility to communicate complex scientific concepts across disciplinesA strong background in quantitative analytical techniquesDemonstrated scientific excellence, as evidenced by publications, external commitments (committees and presentation), and other achievementsA desire to master bioanalytical business processesExcellent scientific problem-solving skillsExcellent project and time management abilitiesAbility to work collaboratively with internal and external stakeholdersWhat you can expect of us As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, we’ll support your journey every step of the way.The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications.In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work / life balance, and career development opportunities that may include : A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accountsA discretionary annual bonus program, or for field sales representatives, a sales-based incentive planStock-based long-term incentivesAward-winning time-off plansFlexible work models, including remote and hybrid work arrangements, where possibleApply now for a career that defies imaginationObjects in your future are closer than they appear. Join us.careers.amgen.com#J-18808-Ljbffr
