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Enzyme Expression Specialist (Temp)

Aralez Bio
Berkeley, CA Temporary
POSTED ON 4/18/2025
AVAILABLE BEFORE 5/17/2025
About the Company

We envision a world where we continuously, sustainably, and affordably improve human life with synthetic biology. Our proprietary set of enzymes and our manufacturing approach enables the production of thousands of amino acids that were previously too difficult and expensive to make. These "noncanonical" amino acids that we make are already catalyzing the creation of revolutionary and innovative products that are good for people and the planet.

Our technology outperforms traditional manufacturing approaches by 10–100x across the board. We already sell products to Big 10 Pharmaceutical companies, and our product family includes the key components of multi-billion dollar blockbuster drugs such as Ozempic and Mounjaro.

We are a diverse, passionate, interdisciplinary team that finds joy in building something new that leaves the world better than we found it. We strive to always learn and improve and have a deep desire to capitalize on our creativity and be exceptional at what we do.

Job Summary

We're seeking a skilled Enzyme Expression Specialist with hands-on experience in microbial protein expression and basic purification techniques. This position will cover essential tasks while an employee is on leave and requires strong manual dexterity, attention to detail, and the ability to work quickly and accurately.

This is an on-site role with a three-month duration (starting ASAP), with potential for conversion to a full time position.

Responsibilities:

Upstream

  • Conduct routine fermentation in bioreactor tanks, including media preparation, tank operation, routine assays, and maintaining thorough documentation per company SOPs.
  • Perform shake flask studies to evaluate and increase enzyme expression and activity for new strains.

Downstream

  • Operate downstream processing equipment, such as centrifuges and TFF systems, to isolate, concentrate, and store protein products.
  • Conduct lyophilization and other standard methods for product preparation.

General

  • Maintain an organized inventory of lab supplies and consumables for both upstream and downstream activities.

Qualifications:

  • BS/BA degree in a science field with at least 2 years of relevant lab experience or AA degree with 3-4 years of fermentation lab experience.
  • Proven ability to follow SOPs with precision, leading to consistently solid results
  • Experience with bioreactor tanks, media prep, shake flask studies, centrifuges, TFF systems, and lyophilizers
  • Solid trouble-shooting, problem solving and written and oral communication skills.

Compensation:

Aralez Bio's wages for this position is $35–$48 per hour, based on your performance and experience. In addition to compensation, this position includes benefits and, if converted to a permanent hire, will also include equity with a vesting start date backdated to your start date for the temp role.

Benefits at Aralez Bio

  • Medical / Dental / Vision coverage
  • 401k
  • Flexible Spending Account
  • PTO and sick time accrual
  • Weekly catered lunch
  • Annual company retreat

Equal Employment Opportunity

Aralez Bio is an equal opportunity employer and does not discriminate based on race, color, religion, marital status, age, national origin, ancestry, physical or mental disability, medical conditions, veteran status, sexual orientation, gender, sex, and any other group protected under federal, state, or local laws.

We celebrate diversity and are committed to creating an inclusive environment for all employees. Please reach out if an accommodation is needed. In compliance with federal law, all persons hired will be required to verify identity and eligibility to work in the United States and to complete the required employment eligibility verification form upon hire.

Salary : $35 - $48

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