Demo

Product Development Scientist II/III

Arima Genomics
Carlsbad, CA Full Time
POSTED ON 1/20/2025
AVAILABLE BEFORE 4/20/2025

Company Description :

Arima Genomics is a San Diego-based startup which is revolutionizing the way Genomic Data is used in basic and disease research. We believe that the state of the art of genomics research, in its 1-Dimensional context, misses the bigger picture, and our technology for capturing chromosome structure will enable a higher dimension of insight into mechanisms of human disease.

Just like our technology is on another level, so are our employees. Our employees are self-reflective and accountable self-starters that are tenacious and relentless in the pursuit of excellent scientific products. They don’t have jobs, they have passion projects!

Our environment is open and collaborative and we invest in each other’s growth and empower one another. We listen to and value differences in perspective and approach.

As a startup, we move fast, adapt to change and are continuously improving ourselves, our processes and our products. Though we are adaptable we constantly prioritize to stay focused on our vision.

How will you make an impact?

This role will develop assays and methodologies for genomic research and diagnostic testing using the Arima Hi-C chemistry. This will involve complex experimental design and DOE for optimization, guardbanding, Stability testing, Repeatability and Reproducibility testing, failure analysis, and Clinical validation. This role will also work with the bioinformatics team to interpret data, Conceive QC metrics and set appropriate spec limits. Additionally, this role will write experimental plans, engineering reports, patents, invention disclosures, user guides, and will be an SME and participate in supporting customers. Some Travel to our Orland, FL facility, Beta testing sites, or conferences will be necessary.

Duties :

  • Assay Development of research and diagnostic tools.
  • Design and execution of experiments to optimize genomics assays and workflows for target specifications and robustness, conduct edge testing, alpha and beta testing, validation and verification testing, reproducibility and repeatability testing, stability testing, and failure analysis
  • Perform statistical analysis of results to aid in interpretation and perform troubleshooting / root cause analyses.
  • Lead or significantly contribute to implementing assay QC metrics and setting appropriate thresholds.
  • Lead or significantly contribute to writing SOPs, user guides, engineering reports, Patent, Invention Disclosures, ect… as needed.
  • Lead or significantly contribute to internal trainings, Customer trainings, webinars, and tech support escalations.
  • Contribute to routine QC testing or small scale manufacturing.
  • Mentor Junior scientist in PD team and across organization.
  • Participate in R&D lab meetings, fostering an environment of intellectual curiosity and critical thinking and collaborate effectively with peers and cross-functional teams across the organization..
  • Participate in additional special team or individual projects.
  • Occasional Travel to Orlando, FL site, Beta testing sites, customer sites for training, and conferences

What we are looking for :

  • A strong interest and belief in the power of genomic structure to revolutionize human disease research and diagnostics
  • Experience developing high quality products.
  • Experience optimizing or developing novel genomics assays assays such as HiC, ChIP, RNA-seq or others as well as next-generation sequencing (NGS) sample prep methods.
  • Experience with statistical tools such as JMP.
  • Great team player who can also work independently.
  • Strong attention to details and excellent written and verbal communication skills.
  • Demonstrated initiative and great organizational skills.
  • Masters of Science with 3-5 years of experience or Ph.D. with 1-3 years of experience in Molecular Biology, Genomics or other related scientific field
  • Arima Genomics believes that everyone has the ability to contribute to company success, and we are committed to providing employment opportunity regardless of sex, race, creed, color, gender, religion, marital status, domestic partner status, age, national origin or ancestry, physical or mental disability, medical condition, sexual orientation, pregnancy, military or veteran status, citizenship status, and genetic information.

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