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Senior Research Associate III, Early Discovery, CAR T Cell Therapy (24213-U-670-EDIS)

Arsenal Biosciences
South San Francisco, CA Full Time
POSTED ON 1/24/2025
AVAILABLE BEFORE 3/24/2025

WHO WE ARE

Arsenal Biosciences Inc. is a clinical-stage programmable cell therapy company engineering advanced CAR T-cell therapies for solid tumors. We are seeking a talented Senior Research Associate III, Early Discovery to work onsite based in our SOUTH SAN FRANCISCO office. 


ArsenalBio’s mission and purpose is very clear: defeat cancer. With our programmable and computationally driven approach, our team is engineering medicines with the goal to attack cancer’s inherent multifaceted nature and overcome the challenges of addressing solid tumors with cell therapy.


Driven by a collective of diverse experts across multi-scientific disciplines as well as clinical and manufacturing expertise, we are united in our purpose to develop the optimal medicines for improving patients’ lives.


This means you’ll have the opportunity to work with the best talent in the field of cell therapy, and be part of ONE TEAM advancing therapies for patients who need it most.


We’re looking for a stellar Senior Research Associate to drive pioneering work in early discovery, and developing next-generation CAR T cell therapies for cancer. If you have a background in synthetic biology, immunology, or cellular/cancer biology and thrive on solving challenging problems with fresh ideas, this is the role for you! As a collaborative communicator, you’ll work across multiple disciplines with a talented, diverse team, pushing the limits of science in a fast-paced, cutting-edge environment. Bring your passion and expertise to help shape the future of cell therapy—join us to make a real impact in the fight against cancer!


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WHAT YOU’LL DO
  • Generate engineered T cells to support in-vitro and in-vivo functional assays
  • Design and execute in vitro functional assays (co-culture, cytotoxicity, proliferation. etc) using genetically engineered T cells to support diverse projects
  • Run multicolor flow cytometry panels to assess phenotypic characteristics of tumor and/or immune cells
  • Get exposed to and support synthetic immunology construct design needs.
  • Support NGS efforts including library construction, sample QC, and executing sequencing runs
  • Summarize and synthesize data across experiments and present findings to colleagues, including diverse management teams
  • Work successfully in matrix organizations via the contribution of data, ideas, and presentations
  • Work with interdisciplinary teams including automation, NGS and compbio to establish and test novel logic-gated CAR T cell designs to enhance cell therapy


WHO YOU ARE
  • Master’s in immunology, cell biology, or related field with 2 years of research experience, or Bachelor’s in the same fields with 4 years of research experience.
  • Experience with general molecular biology techniques
  • Interest in working in a team setting and developing as a scientist both technically and conceptually
  • Aseptic culture technique and experience handling primary and transformed mammalian cells
  • Experience with multiparameter flow cytometry, ELISAs, and high throughput assays using luminescence, fluorescence or UV-visible absorbance
  • Data analysis experience using tools such as FlowJo and GraphPad Prism 
  • Demonstrated ability to work well in a highly collaborative team environment
  • Willingness to accept other responsibilities outside of the initial job description
  • Strong organizational, record-keeping, and communication skills with the ability to quickly learn, stay productive, and deliver high-quality results.
  • Experience with automation or high throughput assays is a plus
  • Experience with data analysis using Python or R is a plus


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BENEFITS AND PAY

ArsenalBio has a generous and comprehensive benefits package that includes but is not limited to medical, dental, and vision as well as mental health resources, virtual and telehealth options, coaching, infertility treatment, parental leave and health savings accounts. We also offer flexible work schedules and flexible time off, which includes two extra “Arsenal Days of Rest” every quarter for employees to recharge. 


Our people-first culture fosters a deep appreciation for humanity, both in the people we endeavor to serve as well as each other. We are proud to work for a company that is driven by diversity in experiences, ideas and interests, and one that empowers us in an environment that embraces both unity and inclusivity.


We have robust tools to help employees take control of their career paths and grow into their best selves. ArsenalBio believes in investing in the well-being of our employees - both at work and at home, as our people are our greatest asset. They bring scientific talents in molecular biology, immunology, pharmacology, protein chemistry, computational biology, automation, genome engineering, software and other fields to make the future happen now.


We are committed to hiring the best talent from diverse backgrounds. A diverse workforce engenders richness of thought, creativity and discovery. We invite individuals who embrace intellectual achievement to bring their unique personal and professional journeys and together we will build transformative cell therapies for cancer patients.


We are an equal opportunity employer and value diversity at our company. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.


The estimated base salary for the preferred primary location of the San Francisco Bay area ranges from $102,000- $125,000. Salary ranges for other locations may vary.  Base pay offered may vary based on job related knowledge, experience, education, and location.  In addition to these factors, we believe in the importance of pay equity and consider internal equity of our current employees as part of any final offer.


To all recruitment agencies: ArsenalBio does not accept agency resumes. Please do not forward resumes to our jobs alias, or ArsenalBio employees. ArsenalBio is not responsible for any fees related to unsolicited resumes.


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Salary : $102,000 - $125,000

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