Intern- Product Development

Asklepios BioPharmaceutical, Inc. (AskBio) is a leading, clinical-stage gene therapy company founded in 2001 based on the work of adeno-associated virus (AAV) gene therapy visionary and pioneer, Jude Samulski, PhD. Since that time, our commitment to developing life-saving medicines that can potentially cure genetic diseases has never wavered. 

At AskBio, we’ve built a foundation of therapeutic programs, AAV manufacturing and a rich portfolio of patented technology. Our therapeutic focus includes neuromuscular, central nervous system, cardiovascular and metabolic diseases with clinical trials underway for Pompe disease, Parkinson’s disease, and congestive heart failure. Our gene therapy platform includes Pro10™, an industry-leading proprietary cell line manufacturing process, and an extensive AAV capsid and promoter library. 

We became a wholly-owned, independently operated, subsidiary of Bayer AG in late 2020 as a cornerstone of its newly formed Cell & Gene Therapy (CGT) platform. Our global headquarters is in Research Triangle Park, NC. Additionally, we have significant operations in Philadelphia, PA, Columbus, OH, Scotland, France, Germany, and Spain.

Our vision: Pioneering science to create transformative molecular medicines.

Our mission: Lead innovative science and drive clinical outcomes to transform people's lives.

Our principles:

• Advance innovative science by pushing boundaries. 

• Bring transformative therapeutics to patients in need.  

• Provide an environment for employees to reach their fullest potential.  

Our values:

• Be a Pioneer. We are not afraid of the impossible and to innovate to make gene therapies accessible to those in need.

• Cultivate Collaboration. Strive to be the best teammate, actively listen, openly communicate, and embrace diverse points of view.

• Embrace Responsibility. We are humbled by the enormity of our mission.  We hold a relentless commitment to advance science and clinical outcomes for our patients, families, and caregivers.

• Raise the Bar. Continuously drive improvements and efficiencies. Seek and provide constructive feedback. Have a bias for learning and action.

• Act with Uncompromising Integrity. Be honest, transparent, and committed to doing what’s right in every situation. Make clear commitments and follow through.

Position Summary

The Intern-Product Development will work closely with members of the Core to develop methods using bioinformatics tools to analyze data generated through the Xenium platform of in situ transcriptomics assays. We are looking for candidates who possess a strong foundation in biology and computer science, with a desire to learn and grow.

This position is based in RTP, North Carolina and reports to the Senior Scientist, Group Lead of the Cellular Biodistribution Core.

Job Responsibilities

• Conduct research and analysis using bioinformatics tools and techniques

• Collaborate with team members to develop and implement bioinformatics workflows

• Process and analyze large datasets to generate meaningful insights

• Communicate effectively with team members to ensure project goals are met

• Maintain accurate and organized records of research findings

• Adhere to company standards and regulations

• Participate in team meetings and provide updates on project progress

• Collaborate with other departments and teams to support cross-functional projects

• Follow best practices for data management and analysis

• Assist in the preparation of reports and presentations to share research findings

• Contribute ideas and suggestions for improving processes and workflows

Minimum Requirements

• Must be pursuing a MS degree in bioinformatics, computational biology, or relevant field.

• Experience with Linux environments

• Experience with R programming language

• Knowledge and experience with single-cell RNAseq and spatial transcriptomic platforms, 10x Genomics Xenium/Visium, Nanostring CosMx Spatial Molecular Imager, Akoya CODEX, or Vizgen MERSCOPE

• Knowledge of molecular biology, genomics, cell and gene therapy

Preferred Education, Experience and Skills

• Experience with image analysis

• Knowledge of Seurat

• Excellent verbal and written communication skills

• Available to work full-time during the summer months (May-August)

• Proactive and solution-driven mindset

• Strong sense of accountability and ability to prioritize multiple tasks

• Excellent organizational skills and attention to detail

• Problem solving skills

• Experience with version control software and practices

• Experience with high performance computing (HPCs) / Amazon Web Services (AWS)

• Familiarity with electronic lab notebook (ELN) usage

Asklepios BioPharmaceutical, Inc. (AskBio) is an Equal Opportunity Employer and does not discriminate against any employee or applicant for employment because of race, color, religion, gender, sexual orientation, gender identity, national origin, age, disability, veteran status or any other protected status prohibited under Federal, State or local laws. All employment decisions are based on valid job‐related requirements. If you are a qualified individual with a disability or a disabled veteran and are unable or limited in your ability to use or access our website, you may request a reasonable accommodation to express interest in a specific opening by calling us at (919) 561-6210 or sending us an email at careers@askbio.com.

Agencies:  Please do not contact any employee at AskBio about this requisition.  Any resume submitted by a recruitment agency to any employee at AskBio, through any medium, will be deemed the sole property of AskBio unless the agency was engaged by AskBio Talent Acquisition team to recruit for that position.  All agencies must have a prior executed service agreement with AskBio prior to any search engagement.  If a candidate who was submitted outside of the AskBio agency process is hired by AskBio, no fee or payment of any kind will be paid to the agency.