What are the responsibilities and job description for the Global Translational Medicine Lead, Oncology position at Astellas?
Do you want to be part of an inclusive team that works to develop innovative therapies for patients? Every day, we are driven to develop and deliver innovative and effective new medicines to patients and physicians. If you want to be part of this exciting work, you belong at Astellas!
Astellas Pharma Inc. is a pharmaceutical company conducting business in more than 70 countries around the world. We are committed to turning innovative science into medical solutions that bring value and hope to patients and their families. Keeping our focus on addressing unmet medical needs and conducting our business with ethics and integrity enables us to improve the health of people throughout the world. For more information on Astellas, please visit our website at www.astellas.com .
This position is based in Cambridge, MA. Remote work from certain states may be permitted in accordance with Astellas’ Responsible Flexibility Guidelines. Candidates interested in remote work are encouraged to apply.
Purpose and Scope :
Lead the development and execution of Translational Medicine strategy in development of Astellas’ assets. Candidates should have record of accomplishment of developing and executing translational science / medicine programs with mechanistically grounded biomarker and patient selection strategies. Ability to work in cross-functional teams is essential to the success of this position.
Essential Job Responsibilities :
- Develops and executes translational science and biomarker development plans and define patient selection strategies for clinical studies
- Provides key specifics on the mechanism of action, biomarker identification and patient selection strategies
- Contributes to overall development strategy and trial design, incorporating biomarker endpoints
- Works with clinical team for implementation of biomarker sample collection and bioanalysis
- Drives clinical biomarker data analysis and interpretation
- Contributes to clinical documents : protocols, IBs, study reports, statistical analysis plans, publications, CSR and biomarker sections of regulatory submissions
- Leads reverse translation, so that clinical results can be used to inform development strategy
- Contributes to greater understanding of the mechanism of action to enable clinical translation
- Thinks strategically and drives innovation. Identifies and leads the evaluation of state -of- the- art technologies for translational and biomarker research
- Establishes and leads Translational Medicine focused external collaborations
