What are the responsibilities and job description for the Associate Scientist, Process Development position at AstraZeneca GmbH?
Introduction to role :
Read the overview of this opportunity to understand what skills, including and relevant soft skills and software package proficiencies, are required.
Join our dynamic team at AstraZeneca as an Associate Scientist, Process Development in Process Development. Based in Santa Monica, CA, you will be supporting and contributing to the design and execution of studies to develop and optimize clinical manufacturing processes of Neogene portfolio of engineered T cell therapies. This role reports to the Senior Scientist, Process Development.
Accountabilities :
You will manage process development studies to develop, optimize, scale-up and transfer cGMP manufacturing processes. You will carry out flow cytometry and cell-based assay experiments for the characterization and optimization of cell therapy manufacturing processes. You will also perform cell culture of T cells in multiple formats including flasks, bags, and bioreactors. Collaborating within the project team to interpret study results and contribute to technical discussions for subsequent study design is also part of your role. You will prepare and review experimental proposals, technical reports, SOPs and manufacturing batch records. Working collaboratively within the PD group and cross-functionally with other groups to meet Technical Operation organization goals is essential.
Essential Skills / Experience :
- A minimum of 6 months practical experience with Flow Cytometry
- Hands-on experience in primary cell culture, specifically in T cells is highly desirable
- Knowledge of cGMP manufacturing and regulations and practical experience in GMP operations is highly desirable
- Knowledge of statistical analysis for process development
- Ability to think critically, analytically and have demonstrated troubleshooting and problem-solving skills based on deductive reasoning
- MS degree in Immunology, Cell Biology, Molecular Biology, Bioengineering, or relevant degrees or similar BS degree with 1.5 years relevant experience within the pharmaceutical or biotech industries
Are you ready to be challenged in your everyday work? Do you have the drive and determination to overcome barriers and make things happen? If so, apply today and join us in making a difference!
The hourly rate of compensation for this position ranges from $34.23 to $51.35 per hour. Hourly and salaried non-exempt employees will also be paid overtime pay when working qualifying overtime hours. Base pay offered may vary depending on multiple individualized factors, including market location, job-related knowledge, skills, and experience. In addition, our positions offer a short-term incentive bonus opportunity; eligibility to participate in our equity-based long-term incentive program (salaried roles), to receive a retirement contribution (hourly roles), and commission payment eligibility (sales roles). Benefits offered included a qualified retirement program [401(k) plan]; paid vacation and holidays; paid leaves; and, health benefits including medical, prescription drug, dental, and vision coverage in accordance with the terms and conditions of the applicable plans. Additional details of participation in these benefit plans will be provided if an employee receives an offer of employment. If hired, employee will be in an “at-will position” and the Company reserves the right to modify base pay (as well as any other discretionary payment or compensation program) at any time, including for reasons related to individual performance, Company or individual department / team performance, and market factors.
J-18808-Ljbffr
Salary : $34 - $51
