What are the responsibilities and job description for the Senior Principal Analytical Scientist – Mass Spectrometry position at Atum - DNA 2.0?
ATUM is seeking an experienced and highly skilled Mass Spectrometry (MS) Scientist to join our analytical team. The ideal candidate will play a key role in advancing analytical methodologies to support large molecule characterization and quality assessment of internal R&D and client projects. The successful candidate will be an integral part of ATUM’s analytical team, driving method development, troubleshooting, and robust data analysis to interrogate and / or ensure product quality and release testing. Key Responsibilities : Develop and optimize MS methods for qualitative and quantitative analysis, ensuring high sensitivity and reproducibility. Perform data acquisition, processing, and interpretation of MS datasets to support research, development, and product services. Develop and execute analytical MS methods, including, but not limited to : Peptide mapping and liability assessment Glycan Profiling Reduced / Intact Mass Ensure appropriate maintenance of assigned equipment, conduct training, and scope process optimization with a “continuous improvement” mindset. Contribute more broadly to ATUM's analytics ecosystem, with a focus on delivering a best-in-class analytics platform for addressing client needs. Prepare and review technical reports, method protocols, and analytical documentation in compliance with regulatory guidelines. Develop custom analytical services upon request. Active participation / lead technical projects within the group. Train and mentor junior team members in analytical techniques and data analysis best practices. Required Qualifications : Ph.D. in Analytical Chemistry, Biochemistry, or a related discipline with 2 years of industry experience; OR M.S. with 5 years of relevant experience. Extensive expertise in LC-MS method development and troubleshooting for characterization of biomolecules, including comprehensive experience with complex large molecule characterization that includes detailed liability and PTM assessment / QC of in-process and fully purified products. A robust practical understanding of large molecules and their respective stage-appropriate analytical methods. Proficiency in data analysis software (e.g., Protein Metrics, MassLynx, Xcalibur, Analyst, Chromeleon, Empower, etc.). Excellent problem-solving skills with the ability to design experiments, analyze data, and interpret results. Strong written and verbal communication skills to effectively document and present findings. Preferred Qualifications : Familiarity with automation and high-throughput analytical workflows, in particular to their application with MS sample prep, data acquisition and analysis. An understanding of FPOP, HDX, and / or other MS techniques used to map protein surface topology, study protein dynamics and interactions. Ability to write scripts for developing customized methods and analyses. Demonstrated ability to work in a fast-paced, collaborative environment. Benefits
- Be part of the next gen biotech revolution
- Excellent growth opportunities
- Great Compensation &benefits package Powered by JazzHR
