What are the responsibilities and job description for the Sr. Associate Scientist/Scientist (I), Analytical Development position at Aura Biosciences?
About Aura Biosciences
Aura Biosciences is a clinical-stage biotechnology company focused on developing precision therapies for solid tumors that aim to preserve organ function. Our lead candidate, bel-sar (AU-011), is currently in late-stage development for primary choroidal melanoma and in early-stage development in other ocular oncology indications and bladder cancer. Aura Biosciences is headquartered in Boston, MA. Our mission is to grow as an innovative global oncology company that positively transforms the lives of patients.
For more information, visit aurabiosciences.com. Follow us on X (formerly Twitter) @AuraBiosciences and visit us on LinkedIn.
Position Summary
The Sr. Associate Scientist/Scientist (I) will play a key role in achieving Analytical Development (AD) objectives to support Aura Biosciences' mission of developing safe and effective therapies using virus-like particle (VLP)-based technologies. This position involves spending over 80% of the time at the bench, primarily providing analytical results in support the process team.
Overall Responsibilities
Knowledge, Skills & Capabilities:
Open to travel to CTLs and CDMOs, as needed (
Salary & Benefit Information
Salary Range: $65,000/yr - $130,000/yr
(Placement within the listed range depends on many factors including, but not limited to: geographic location, degree, years of experience, and internal company equity.)
Aura Biosciences is a clinical-stage biotechnology company focused on developing precision therapies for solid tumors that aim to preserve organ function. Our lead candidate, bel-sar (AU-011), is currently in late-stage development for primary choroidal melanoma and in early-stage development in other ocular oncology indications and bladder cancer. Aura Biosciences is headquartered in Boston, MA. Our mission is to grow as an innovative global oncology company that positively transforms the lives of patients.
For more information, visit aurabiosciences.com. Follow us on X (formerly Twitter) @AuraBiosciences and visit us on LinkedIn.
Position Summary
The Sr. Associate Scientist/Scientist (I) will play a key role in achieving Analytical Development (AD) objectives to support Aura Biosciences' mission of developing safe and effective therapies using virus-like particle (VLP)-based technologies. This position involves spending over 80% of the time at the bench, primarily providing analytical results in support the process team.
Overall Responsibilities
- Deliver analytical results promptly to the process team using analytical methods pertinent to the qualitative and quantitative characterization of biologic test samples.
- Conduct routine analytical testing and method development projects, as needed.
- Maintain high quality documentation and records in electronic lab notebooks following good laboratory practices.
- Troubleshot analytical methods.
- Perform data trending and analysis using logistic fitting methods, including software for statistical analysis and presentation.
- Author technical protocols and reports, assay summaries, study design and protocols, SOPs, as required.
- Establish and maintain familiarity with contemporary industrial standards, practices, technologies, literature, and ways of performing lab studies.
Knowledge, Skills & Capabilities:
- Expertise in biophysical analysis of virus-like particles (VLPs) is preferred.
- Analytical understanding of various Biologic modalities (e.g., mAb, antibody-drug conjugate, fusion protein) is desired.
- Experience in LC workflows and a strong fundamental understanding of separation science, chromatography, and column-method development is required
- Working knowledge of analytical instrumentation: SE-HPLC, RP-HPLC, DLS, NTA, flow imaging, fluorometry, and other particle-based technologies is desired.
- Knowledge and firsthand experience in one or more of the following areas involving biological molecules: ELISA, gel electrophoresis (SDS/WB), plate-based spectroscopy (UV/Vis), binding affinity, SPR, flow cytometry, Octet, and other biological methodologies is preferred.
- Capable of managing priorities, effectively communicating across development teams, and meeting deadlines within tight timelines.
- Once fully trained can function independently or under minimal supervision.
- Fundamental understanding of method development, qualification, and transfer of analytical methods.
- Effective communication, critical thinking, technical writing, and critical thinking skills
- Working knowledge of statistical methods for data analysis (e.g., JMP) is a plus.
- Problem solving ability for issues related to analytical development and sample testing.
- Ability to draft accurate protocols/reports.
- A BSc degree in a relevant scientific discipline e.g., Analytical Chemistry/Biochemistry, or MSc or BSc with 2 years of biotech industry experience.
- Experience in handling and testing protein samples to support process development. Familiarity with drug conjugates and viral particles is advantageous.
Open to travel to CTLs and CDMOs, as needed (
Salary & Benefit Information
Salary Range: $65,000/yr - $130,000/yr
(Placement within the listed range depends on many factors including, but not limited to: geographic location, degree, years of experience, and internal company equity.)
- Health insurance with FULL premium coverage
- 401K with company match
- Employee Stock Purchase Program (ESPP)
- Competitive Paid time off (PTO)
- Company-paid short & long-term disability insurance and life insurance
Salary : $65,000 - $130,000
