Program Team Lead - AVD-104

Aviceda Therapeutics is a private clinical-stage biotech company focused on the next generation of glyco-immune therapeutics that leverage the Glyco-Code® technology platform to address inflammatory diseases of the innate immune system including geographic atrophy (GA) from age-related macular degeneration (AMD), cancer, fibrosis, neurologic diseases, and others. 

At Aviceda, we exploit a unique family of receptors expressed on all innate immune cells, and their associated glycobiological interactions, to develop transformative medicines for a variety of pathologies with current unmet needs. We combine the power of our biology with our innovative cell-based high-throughput screening platform and proprietary nanoparticle technology to modulate the immune response specifically and profoundly. 

Aviceda has assembled a world-class, cross-disciplinary team of recognized scientists, clinicians, and drug developers to tackle devastating ocular and systemic degenerative, fibrotic, and immuno-inflammatory diseases. Our primary offices and lab are based in Cambridge, Massachusetts.

Overview:

Aviceda Therapeutics is seeking a Program Team Leader (PTL) to lead the AVD-104 program through clinical phases and commercialization. AVD-104 is currently in a phase 2 clinical study and will soon enter a phase 3 and subsequent clinical, CMC, regulatory activities. The PTL will lead program/project activities and execution of the current plans within established timelines and budget while planning for clinical studies, global regulatory filings and pre-commercial activities. This individual will provide leadership across the spectrum of drug development activities, ensuring the achievement of both program and Aviceda goals. The ideal candidate will be a strategic and entrepreneurial leader that is well-versed in drug development. This individual will be a strong influencer who can integrate multiple perspectives effectively, align stakeholders across functions and organization levels, problem solve and achieve the program goals.

Summary of Key Responsibilities:

·      Work collaboratively and cross-functionally with Clinical Operations, Research, Regulatory Affairs, CMC, Manufacturing, Quality Assurance, Drug Safety, Finance, and other team members to deliver program goals within established timelines and budget.

·      Leverage past experience to build and advance Aviceda’s systems

·      Drives decision-making and issues resolution within the team and through the governance process

·      Expected to identify bottlenecks, surface issues, and proactively drive for their resolution, and to lead contingency planning efforts

·      Leads ad-hoc cross-functional task forces, as needed, aiming at issue resolution or organizational efficiency

·      Manages project variance and root cause analysis, develops risk mitigation/ issue management plans with the objective to meet the financial targets

·      Working with functional leaders, ensure that appropriate prioritization and adequate resource allocation (financial and personnel) are present to meet the program timelines and deliverables.

·      Serve as an internal and external ambassador for the program, fostering broad engagement to cultivate strategic relationships and enabling overall integration of external insights to inform program strategies.

·      Summarize and represent the program status to Aviceda leadership, Board of Directors, collaborators, and other external parties, as requested.

Qualifications:

·      BA/BS degree required; advanced medical, scientific or business degree strongly preferred.

·      12 years biopharmaceutical experience with previous program leadership responsibilities; demonstrated experience leading cross-functional teams in drug development.

·      Deep understanding of drug development and global product registration is required with late phase and commercialization considered a plus. Leadership of a recent successful program (positive pivotal data, regulatory approval, etc.) would be ideal.

·      Proactive “hands-on” individual with collaborative orientation, who manages teams effectively, is very self-motivated, entrepreneurial and can smoothly establish strong working relationships within both internal and external organizations.

·      Problem solver. Achieves goals within timelines and budgets while anticipating and navigating obstacles effectively.

·      Exceptional written and verbal communication skills; able to articulate program vision and motivate the team; communicates in an open, direct and timely manner; ensures broader organization is aligned with and aware of the program strategy, status and potential risks.

·      Motivated by patient focus and personal commitment to high performance and results.

·      Possesses high integrity and exceptional work ethic.

·      Ability to think strategically and solve problems effectively.

·      Commitment to fostering a collaborative and inclusive work environment.

Aviceda Therapeutics is an equal opportunity employer offering competitive cash and stock compensation, excellent employee benefits, and the opportunity for personal and professional growth in an outstanding and intellectually challenging environment.