Strive to Bring a Profound Difference to our Patients

At Avidity Biosciences, we are passionate about the impact of every employee in realizing our vision of improving people’s lives by delivering a new class of RNA therapeutics. Avidity is revolutionizing the field of RNA with its proprietary AOCs, which are designed to combine the specificity of monoclonal antibodies with the precision of oligonucleotide therapies to address targets and diseases previously unreachable with existing RNA therapies. If you are a committed, solution-oriented thinker, join us in making a difference and become part of our growing culture that is integrated, collaborative, agile and focused on the needs of patients. 

Avidity Biosciences, Inc.'s mission is to profoundly improve people's lives by delivering a new class of RNA therapeutics - Antibody Oligonucleotide Conjugates (AOCs™). Utilizing its proprietary AOC platform, Avidity demonstrated the first-ever successful targeted delivery of RNA into muscle and is leading the field with clinical development programs for three rare muscle diseases: myotonic dystrophy type 1 (DM1), Duchenne muscular dystrophy (DMD) and facioscapulohumeral muscular dystrophy (FSHD). Avidity is broadening the reach of AOCs with its advancing and expanding pipeline, including programs in cardiology and immunology through internal discovery efforts and key partnerships. Avidity is headquartered in San Diego, CA. For more information about our AOC platform, clinical development pipeline, and people, please visit www.aviditybiosciences.com and engage with us on LinkedIn and Twitter.

The Opportunity

We are seeking a highly motivated and independent Senior Research Associate to join our Bioanalytical Team and contribute to our understanding of antibody oligonucleotide conjugates. This is a hands-on position with responsibilities that require daily lab work, data analysis, and interpretation of data that will be shared with cross-functional teams and key stakeholders. The ideal candidate will be proficient in areas of bioanalysis that include LCMS, ELISA, HPLC, and/or RT-qPCR, organized and independent, a strong team player, and have great verbal and written communication skills.

What You Will Contribute

• Hands-on lab work with responsibility for processing and analyzing in vivo study samples.
• Design and perform experiments, analyze experimental data, report results, and provide feedback on appropriate next steps such as assay optimization or follow-up experiments.
• Assist in developing novel methods of bioanalysis to support nonclinical and clinical studies, with an emphasis on quantification of antibody-oligonucleotide conjugates and their components.
• Maintain relationships with external service providers, facilitating method transfer, method development, method validation, and sample analysis in a GLP environment.
• Demonstrate effective time management skills and adhere to provided timelines.
• Keep detailed and accurate records in an electronic laboratory notebook. Demonstrate effective presentation and verbal communication at internal meetings as well as clear written communication.
• Ensure GxP and SOP training tasks are completed in a timely manner.
• Perform other duties as required.

What We Seek

• BS or MS in Biology, Biochemistry, or related discipline with at least 2 years of laboratory experience
• Prior hands-on lab experience with various laboratory techniques including RT-qPCR, DNA/RNA isolation, LC-MS/MS, ELISA, siRNA, Kingfisher automation, HPLC, MSD, peptides, biologics
• Prior knowledge in developing bioanalytical assays is preferred
• Ability to conduct self-directed research and to work effectively in a dynamic environment with a diverse team of coworkers
• Solid written and oral communication skills, enthusiasm, integrity, exceptional problem-solving skills, self-motivation, strong interpersonal skills, and attention to detail are necessary
• Demonstrated excellent communication (oral and written), teamwork, organizational, interpersonal, and problem-solving skills

What We Will Provide to You:

• The base salary range for this role is $43/hr. - $48/hr. The final compensation will be commensurate with such factors as relevant experience, skillset, internal equity and market factors.
• Avidity offers competitive compensation and benefits which includes the opportunity for annual and spot bonuses, stock options and RSUs, as well as a 401(k) with an employer match. In addition, the comprehensive wellness program includes coverage for medical, dental, vision, and LTD, and four weeks of time off.
• A commitment to learning and development which includes a variety of programming internally developed by and for Avidity employees, opportunities for job-specific training offered by industry, and an education reimbursement program.