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Principal Scientist: Kidney Disease Research, Computational Biology

BI Pharmaceuticals, Inc.
Ridgefield, CT Full Time
POSTED ON 4/3/2025
AVAILABLE BEFORE 5/14/2025

The Computational Biologist will play a critical role in our kidney disease research program and will join our innovative Computational Biology and Digital Sciences (CBDS) department at Ridgefield, CT. This position involves the application of computational and bioinformatics techniques to identify and validate new therapeutic targets for kidney disease. The successful candidate will work closely with cross-functional teams, including geneticists, biologists, and chemists, to drive the discovery and development of novel treatments.

As an employee of Boehringer Ingelheim, you will actively contribute to the discovery, development, and delivery of our products to our patients and customers. Our global presence provides opportunity for all employees to collaborate internationally, offering visibility and opportunity to directly contribute to the companies' success. We realize that our strength and competitive advantage lie with our people. We support our employees in a number of ways to foster a healthy working environment, meaningful work, diversity and inclusion, mobility, networking and work-life balance. Our competitive compensation and benefit programs reflect Boehringer Ingelheim's high regard for our employees.

Duties & Responsibilities

  • Develop and implement computational models and algorithms to analyze large-scale genomic, transcriptomic, and proteomic data.
  • Identify and prioritize potential therapeutic targets for kidney disease through integrative data analysis.
  • Collaborate with experimental biologists to design and interpret validation studies.
  • Utilize machine learning and artificial intelligence techniques to enhance target discovery processes.
  • Stay current with the latest advancements in computational biology and kidney disease research.
  • Prepare and present research findings to internal teams, external collaborators and through publications and meeting presentations.

Requirements

  • Ph.D. degree or equivalent from an accredited institution in Computational Biology, Bioinformatics, Systems Biology, or a related field.
  • 5 or more years of relevant industry experience in discovery research with deep understanding of cardiometabolic-renal diseases after completing a doctoral degree, with at least two (2) years’ experience in drug discovery, strongly preferred.
  • Strong background in computational and statistical methods for biological data analysis.
  • Proficiency in programming languages such as Python, or R using cluster and/or cloud infrastructure, together with data visualization frameworks ( e.g., ggplot2, matplotlib etc.).
  • Experience with high-throughput data analysis and integration including single-cell and spatial RNA-Seq / proteomic data.
  • Excellent problem-solving skills and the ability to work independently and collaboratively.
  • Strong communication skills, both written and verbal.
  • Track record of scientific publications in peer-reviewed journals.

Preferred Qualifications:
  • Knowledge of kidney disease biology and related pathways is highly desirable.
  • Experience with machine learning, LLM integration and other AI applications in biological research.
  • Familiarity with drug discovery and development processes.

Eligibility Requirements:
  • Must be legally authorized to work in the United States without restriction.
  • Must be willing to take a drug test and post-offer physical (if required)
  • Must be 18 years of age or older

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