Clinical Scientist

Position Overview:

This position supports the scientific planning and execution of one or more clinical trials or significant aspects thereof.  In this position, you will have the opportunity to demonstrate your technical skills, and scientific acumen as part of a global, cross-functional team. Responsible for leading specific aspects of clinical/scientific execution of clinical protocol(s).

Responsibilities:

• Serve as clinical scientist on the clinical trial team.
• Support the medical monitoring team in review and interpretation of clinical data and medical protocol deviations.
• Provide data review per Data Review Guideline to ensure high-quality data of the study on an ongoing basis.
• Collaborate cross-functionally in the development of study protocol and related study materials (e.g., ICF documents/amendments); Partner with Clinical Operations on study deliverables.
• Provide study related data to support regulatory documents (e.g., investigator brochure).
• Ensure CRF design supports data collection in alignment with the protocol in collaboration with Data Management/Programming.
• Support site initiation activities and interactions with site staff.
• Collaborate cross-functionally to monitor clinical data to ensure quality, completeness, and integrity of trial conduct.
• Support investigator meeting(s), IDMC meeting(s) and thought leader interactions.

Qualifications:

• Degree in life sciences (such as medicine, pharmacy, biology) with at least 3-years’ experience in clinical research/development required.
• Advanced degree (MD, PhD, PharmD or Master’s Degree) with at least 2-years’ experience in clinical oncology research/development preferred, but not required.
• Basic knowledge of clinical research regulatory requirements (e.g., GCP and ICH).
• Ability to manage multiple competing priorities with good planning, time management and prioritization skills.
• Strong analytical skills with the ability to interpret clinical trial data and synthesize conclusions.
• Interact with key stakeholders across department, division, and company to achieve study goals with high quality and during the agreed time.
• Problem solving, prioritization, conflict resolution, and critical thinking skills.
• Strong communication, technical writing, and presentation skills.
  
  

Company Overview

Bicara Therapeutics is a clinical-stage biopharmaceutical company committed to bringing transformative bifunctional therapies to patients with solid tumors. Bicara’s lead program, ficerafusp alfa, is a bifunctional antibody that combines two clinically validated targets, an epidermal growth factor receptor (EGFR) directed monoclonal antibody with a domain that binds to human transforming growth factor beta (TGF-β). Through this dual-targeting mechanism, ficerafusp alfa has the potential to exert potent anti-tumor activity by simultaneously blocking both cancer cell-intrinsic EGFR survival and proliferation, as well as the immunosuppressive TGF-β signaling within the tumor microenvironment. Ficerafusp alfa is being developed in head and neck squamous cell carcinoma, where there remains a significant unmet need, as well as other solid tumor types. For more information, please visit www.bicara.com or follow us on LinkedIn or X.

Here at Bicara, we believe in building diverse teams and cultivating a culture where all voices are included. We encourage people from all backgrounds to apply. 

Bicara Therapeutics is an equal opportunity employer and will not discriminate against any employee or applicant on the basis of age, color, disability, gender, national origin, race, religion, sexual orientation, veteran status, or any classification protected by federal, state, or local law.