Senior Bioinformatics Engineer, Oncology

BillionToOne is a next-generation molecular diagnostics company dedicated to developing powerful and accurate diagnostic tests that are accessible to all. Our innovative QCT molecular counting technology significantly enhances the resolution of disease detection using cell-free DNA by over a thousandfold. This groundbreaking technology is integral to our product offerings, including one of our flagship products, Unity Complete™, the only non-invasive prenatal screen capable of assessing fetal risk for both common recessive conditions and aneuploidies from a single maternal blood sample. Leveraging the same molecular counting technology, we've expanded our impact into oncology in 2023 with a pioneering liquid biopsy test, Northstar, that combines treatment selection with monitoring. To date, over 500,000 patients have benefited from our innovative and precise diagnostic tests, and our Annual Recurring Revenue (ARR) has grown from $0 to $125 million in the last ~4 years.

BillionToOne has successfully raised close to $400 million in funding, with a notable $130 million Series D round completed in June 2024, resulting in a company valuation of over $1 billion. This funding has come from prestigious global institutional investors, including Hummingbird, Adams Street Partners, Neuberger Berman, Baillie Gifford, and Premji Invest. BillionToOne has recently been recognized by Forbes as one of America's Best Startup Employers for 2024, highlighting the company's exceptional work environment and commitment to innovation.

Our team has grown significantly and we now proudly employ over 500 highly skilled individuals. Despite substantial growth, we have successfully maintained the unique culture that has defined BillionToOne from inception, continuing to cultivate a team that is not only diverse and passionate but also innovative. Headquartered in Menlo Park, California, with an additional facility in Union City, California, BillionToOne remains at the forefront of significant advances in molecular diagnostics, evidenced by the recent announcement of clinical outcomes data for its Unity Fetal Risk Screen and new advancements in cancer diagnostics. For more detailed information about BillionToOne and its groundbreaking work, please visit our website at www.billiontoone.com.

We are looking for a Senior Bioinformatics Engineer, Oncology to join a fast growing team. This person will be responsible for the development and maintenance of the clinical bioinformatics pipelines and workflows. Our sample volume is growing extremely quickly and this role will lead the effort in building scalable and reliable software solutions to support this growth. The Senior Bioinformatics Engineer role is a full-time onsite position in our Menlo Park office.

Responsibilities

• Build and maintain reliable and scalable bioinformatics pipelines and workflows for analyzing next generation sequencing (NGS) data
• Build and maintain tests and test frameworks
• Build and maintain CI/CD pipelines for testing and deployment
• Support production operation and troubleshoot production issues
• Create and maintain high quality software documentations
• Comply with and make improvements to software development life cycle (SDLC) and quality management systems
• Collaborate and communicate with other teams on new product development and production operation
  
  

Requirements

• 10 years of post graduate experience in software development, with at least 3 years developing NGS pipelines, preferably in industry. 3 years relevant experience with PhD in a related field.
• Fluency in Python and Linux environment
• Experience with CI/CD pipelines
• Experience with AWS and infrastructure management with infrastructure as code such as CDK
• Excellent verbal and written communication skills, ability to work across functional teams and with non-experts.
  
  

Nice-To-Haves

• Experience working in a regulated environment
• Devops experience
• Experience with ETL pipelines, SQL and database management
• Experience with building web applications
  
  

Benefits And Perks

• Working with a team of ‘rockstars’ who bring out the best in everyone
• Open, transparent culture that includes weekly Town Hall meetings
• The ability to indirectly or directly change the lives of hundreds of thousands patients
• Multiple medical benefit options; employee premiums paid 100% of select plans, dependents covered at 80%
• Extremely generous Family Bonding Leave for new parents (16 weeks, paid at 100%)
• Retirement savings program including a 4% Company match
• Free daily on-site lunches provided from top eateries
• Latest and greatest hardware (laptop, lab equipment, facilities)
• A variety of perks on campus (state of the art gym, restaurant)
• Free on-site EV charging (compatible with all EVs, including Tesla)
  
  

At BillionToOne, we are proud to offer a combination of a (1) base pay range (actual amount offered is based on experience and salary/equity options split that the candidate chooses), (2) generous equity options offering, (3) corporate bonus program, on top of (4) industry leading company benefits (free healthcare options, 401k match, very generous fully paid parental leave, etc.).

For this position, we offer a total compensation package of $235,050 per year, including a base pay range of $153,000 - $173,400 per year.

BillionToOne is an equal opportunity employer. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.

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