Demo

Scientist, Lead Generation Biology

BioPhase Solutions
San Diego, CA Full Time
POSTED ON 1/23/2025
AVAILABLE BEFORE 4/11/2025

Job Description

Job Description

Job Description

We are seeking a motivated, collaborative, and skilled biophysical / SPR scientist to join our innovative team. This role focuses on supporting antibody and peptide discovery initiatives by leveraging label-free technologies such as Biacore and Octet BLI. Core responsibilities include determining binding affinities, off-rates, epitope mapping, and performing competition assays. This laboratory-based position requires strong technical expertise, organizational skills, and the ability to thrive in a cross-functional, fast-paced environment driving therapeutic innovation.

Key Responsibilities

  • Execute experiments using Biacore SPR and Octet BLI to assess biomolecular interactions, including affinity (KD), kinetics, epitope mapping, pH-dependent binding, and dual-target engagement.
  • Analyze data using advanced tools like Biacore Insight and Octet software, applying QC measures and resolving any technical issues.
  • Deliver comprehensive data reports and presentations to facilitate project decision-making.
  • Maintain SPR and BLI instruments, ensuring optimal functionality.
  • Collaborate closely with multidisciplinary teams across therapeutic programs to meet shared research objectives.

Qualifications

General Skills :

  • Comprehensive understanding of scientific methods and experimental design.
  • Excellent teamwork and interpersonal communication abilities.
  • Proficient in software such as Prism, Excel, and Word.
  • Strong problem-solving, analytical, and organizational skills.
  • Detail-oriented with the ability to manage tasks and meet deadlines efficiently.
  • Technical Expertise :

  • Proficiency with Biacore SPR and Octet BLI techniques for characterizing antibody / protein interactions.
  • Experience with epitope mapping and competition assays using BLI platforms.
  • Skilled in data QC, troubleshooting, and instrument maintenance.
  • Personal Attributes :

  • Highly collaborative and adaptable to a fast-moving, research-driven setting.
  • Committed to delivering high-quality results that drive project success.
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