Demo

Scientist (Mass Spectrometry)

BioSpace
South San Francisco, CA Full Time
POSTED ON 2/1/2025
AVAILABLE BEFORE 3/2/2025
Sutro Biopharma, Inc. is seeking a highly motivated and skilled scientist with expertise in mass spectrometry to join our dynamic Research team. In this role, you will leverage advanced analytical techniques to perform detailed characterization and analysis of proteins, with a particular focus on monoclonal antibodies, bispecific antibodies, and antibody-drug conjugates (ADCs). Your work will play a critical role in lead candidates’ selection, enabling the development of innovative biotherapeutics for unmet medical needs. As a key contributor to our team, you will design and implement state-of-the-art mass spectrometry methods to analyze protein modifications and identify impurities, understand the heterogeneity of products, ensuring the quality and efficacy of our therapeutic candidates. You will collaborate closely with cross-functional teams, providing actionable insights that drive decision-making in antibody engineering, process development, and strain engineering. This position offers an exciting opportunity to work at the forefront of biotherapeutics, where your expertise will directly impact on the discovery and development of next-generation medicines. If you are passionate about scientific innovation and thrive in a fast-paced, collaborative environment, we encourage you to join us in pushing the boundaries of therapeutic research and development. Responsibilities

  • Independently perform mass spectrometry assays in support of monoclonal antibody-drug conjugate characterization and process development activities, including but not limited to intact, subunit and peptide level analysis.
  • Ability to serve as an analytical subject matter expert, represent Research and work closely with colleagues across different functional teams and departments.
  • Assist in evaluating new technologies to stay at the cutting edge of biologics discovery, production, and analysis.
  • Participate in cross-functional teams at project-related meetings, lead/facilitate technical discussions.
  • Maintain and troubleshoot instrumentation, including mass specs, and associated LCs, autosamplers.


Qualifications:

  • PhD in analytical chemistry, biochemistry, molecular biology, or a related field with 1 to 3 years of industry experience; BS/MS in chemical biology, biochemistry, chemistry, molecular biology, or a related field with over 6 years of experience in characterizing large molecules.
  • Demonstrated theoretical and practical understanding of scientific discipline with the ability to learn and master innovative technologies.
  • In-depth experience with various mass spectrometry platforms (Orbitrap and Q-ToF), MS workflows for protein characterization, and MS software applications for analyzing both routine and complex data sets.
  • Robust analytical knowledge with demonstrated proficiency of various chromatographic and capillary electrophoresis techniques.
  • Direct experience with biologics, monoclonal antibodies and/or protein therapeutics is a plus.
  • Direct experience in ion mobility technology is a plus.
  • Excellent organizational skills with the capacity to manage multiple projects and tasks simultaneously within timelines.
  • Goal-oriented team player with excellent verbal and written communication skills and a strong can-do attitude and can operate effectively in a fast-paced, multi-disciplinary environment.


Sound exciting? Apply today and join our team!Sutro Biopharma, Inc. encourages all colleagues to be fully vaccinated for COVID-19 prior to the first date of employment. As an equal opportunity employer, we believe in fostering a culture that is inclusive and values diversity in background and opinions. Sutro Biopharma hires extraordinary individuals into every position in the company and is committed to the diversity of our team. Our company progresses without regard to race, ethnicity, gender, sexual orientation, religious belief, age, disability or citizenship status. We are dedicated to creating a safe environment where our employees can grow and succeed together. We look forward to hearing from candidates who are interested in exploring opportunities with Sutro! Our People & Culture team/hiring managers are unable to respond and do not accept solicitations from third-party agencies. The anticipated salary range for fully qualified candidates applying for this role at Sutro Biopharma’s California based locations will be $130,000 to $148,000 (not including bonus, equity, and benefits). The final salary offered will be dependent on several factors that include and are not limited to relevant previous experience, job responsibilities and duration of experience, the type and length of experience within the industry and education. About Sutro Biopharma Sutro Biopharma, Inc., is a clinical-stage company relentlessly focused on the discovery and development of precisely designed cancer therapeutics, transforming what science can do for patients. Sutro’s fit-for-purpose technology, including cell-free XpressCF®, provides the opportunity for broader patient benefit and an improved patient experience. Sutro has multiple clinical stage candidates, including luveltamab tazevibulin, or luvelta, a registrational-stage folate receptor alpha (FRα)-targeting ADC in clinical studies. A robust pipeline, coupled with high-value collaborations and industry partnerships, validates our continuous product innovation. Sutro is headquartered in South San Francisco. For more information, follow Sutro on social media @Sutrobio, or visit www.sutrobio.com.

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