Senior Scientist, Chemistry II

Company Description

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas immunology, oncology, neuroscience, and eye care and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us atwww.abbvie.com. Follow @abbvie onX,Facebook,Instagram,YouTube,LinkedInandTik Tok.

Job Description

The Centralized Organic Synthesis Group (COSG) is a team of synthetic organic chemists that works at the interface between Medicinal and Process Chemistry. The group works directly with small molecule Discovery project teams from pre-Lead Optimization through the clinical candidate nomination process. The team is charged with providing chemistry strategies, novel cores and intermediates for structure-activity relationships, optimized routes for active pharmaceutical ingredient (API) and is expected to be a source for synthetic expertise. As project teams proceed toward a clinical candidate, COSG chemists execute large-scale synthesis campaigns to support preclinical toxicology studies and transfer high-quality synthetic routes to the Process Chemistry team. COSG chemists are exposed to several projects at once and are expected to collaborate with all relevant stakeholders and technical experts to achieve project and Discovery goals. The applicant must have a passion for hands-on synthetic organic chemistry.

Primary Job Function

• Conceive and execute synthetic organic chemistry research and development that achieves project and area goals.
• Provide high-quality intermediates and API for the Medicinal Chemistry teams and toxicology studies.
• Generate new scientific proposals and lead those efforts to advance our understanding of project chemistry. Investigate, identify, develop, and optimize new methods/ techniques.
• Act as a lead scientist in an area of expertise on one or more projects.
• Critically evaluate relevant scientific advances and integrate this knowledge into research programs.
  
  
  

Core Job Responsibilities

• Maintain a high level of productivity in the laboratory.
• Demonstrate the ability to resolve key project hurdles and assumptions by effectively utilizing available information and technical expertise.
• Proactively seek out new information in the literature and incorporate this into individual project(s) as well as the overall program.
• Publish research in peer-reviewed journals and present work at scientific conferences.
• Effectively communicate research and/or other regulatory materials.
• Present research at group and project meetings.
  
  
  

Position Accountability/Scope

• Demonstrate a high degree of responsibility in maintaining scientific standards, and safe laboratory practices.
• Participate in establishing project goals, defining short and long-term chemistry strategies, and contribute to the generation of project-related documents and presentations.
• Keep accurate and current records of research and/or project related activities according to AbbVie policies.
  
  
  

Internal/External Contacts And Interactions

• Use external information to gain competitive intelligence.
• Act as advocate to integrate this knowledge into the group's research efforts.
• Generate new research or development strategies to effectively address project and divisional goals and needs.
• Collaborate with functional and technical experts to facilitate scientific achievement.
• Publish project-related research in high-impact factor peer-reviewed journals, R&D reports, patent applications and/or regulatory documents/filings.
• Act in compliance with applicable Corporate and Divisional Policies and procedures.
  
  
  

Qualifications

Basic Qualifications:

• MS or PhD in Organic Chemistry or related field. Pharmaceutical industry experience working in a synthesis-oriented team is desirable.
• 10 (MS) or 4 (PhD) years of experience.
• Experience executing multi-gram scale synthesis campaigns to support preclinical toxicology studies is highly desirable.
• Experience enabling novel SAR through the synthesis of versatile intermediates is highly desirable.
• Experience interfacing with project teams, including DMPK, toxicology, formulation, etc. with a working knowledge of these cross-functional subjects is desired.
• Excellent practical synthetic organic chemistry and analytical skills.
• Experience in multi-gram synthesis, multi-step synthesis campaigns, and reaction optimization.
• Ability to resolve key project hurdles and assumptions by effectively utilizing available information and technical expertise.
• Strong scientific communication and writing skills.
• Strong desire to collaborate and work in a highly dynamic team setting.
  
  
  

Key Leadership Competencies

• Builds strong relationships with peers and cross functionally with partners outside of team to enable higher performance.
• Learns fast, grasps the "essence and can change course quickly where indicated.
• Raises the bar and is never satisfied with the status quo.
• Creates a learning environment, open to suggestions and experimentation for improvement.
• Embraces the ideas of others, nurtures innovation and manages innovation to reality.
  
  
  

Additional Information

Applicable only to applicants applying to a position in any location with pay disclosure requirements under state orlocal law:

• The compensation range described below is the range of possible base pay compensation that the Companybelieves ingood faith it will pay for this role at the timeof this posting based on the job grade for this position.Individualcompensation paid within this range will depend on many factors including geographic location, andwemay ultimatelypay more or less than the posted range. This range may be modified in thefuture.
• We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick),medical/dental/visioninsurance and 401(k) to eligibleemployees.
• This job is eligible to participate in our short-term incentiveprograms.
• This job is eligible to participate in our long-term incentiveprograms.
  
  
  

Note: No amount of payis considered to bewages or compensation until such amount is earned, vested, anddeterminable.The amount and availability of any bonus,commission, incentive, benefits, or any other form ofcompensation and benefitsthat are allocable to a particular employee remains in the Company's sole andabsolutediscretion unless and until paid andmay be modified at the Companys sole and absolute discretion, consistent withapplicable law.

AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives, serving our community and embracing diversity and inclusion. It is AbbVies policy to employ qualified persons of the greatest ability without discrimination against any employee or applicant for employment because of race, color, religion, national origin, age, sex (including pregnancy), physical or mental disability, medical condition, genetic information, gender identity or expression, sexual orientation, marital status, status as a protected veteran, or any other legally protected group status.

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