Senior Scientist I/II, Biologics Analytical R&D

Company Description

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas immunology, oncology, neuroscience, and eye care and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us atwww.abbvie.com. Follow @abbvie onX,Facebook,Instagram,YouTube,LinkedInandTik Tok.

Job Description

AbbVie Biologics Analytical Research & Development (Biologics Analytical R&D) is a global analytical sciences organization responsible for all CMC analytical activities related to the development of AbbVie's pharmaceutical products. Our scope includes AbbVie's diverse pipeline of innovative therapeutic biologic medicines and spans from the selection of Discovery candidate molecules through the transition of analytical methods and testing to commercial labs to support product launch. We are building a world-class team of scientists and leaders who will drive the advancement of industry-leading analytical capabilities and make meaningful contributions to advance AbbVie's pipeline of innovative medicines. Careers in AbbVie Biologics Analytical R&D provide unique opportunities to work with global and cross-functional teams to drive exceptional science and innovative product development strategies.

The biologics characterization group develops state-of-the-art analytical techniques for in-depth characterization of therapeutic proteins and other novel biologic molecules using separation science, mass spectrometry and other biophysical techniques. We are looking for diverse candidates with strong scientific and leadership experience to join the AbbVie Analytical R&D team and can offer exciting and rewarding career opportunities for these candidates.

The candidate will focus on development and implementation of analytical assays for the deep characterization of complex biologics including antibodies, antibody drug conjugates, gene therapies and oligonucleotide/RNA therapeutics. The candidate will use a variety of analytical techniques including chromatography, electrophoresis, surface plasmon resonance, DLS, AF4, MALS, ELISA, and mass spectrometry. The successful candidate will contribute to the development and testing of complex biophysical assays and will contribute to the continuous improvement and innovation within the group.

Key Responsibilities

• Effectively function as a senior research scientist, generating original technical ideas and research or development strategies.
• Demonstrate the ability to resolve key project hurdles and assumptions by effectively utilizing available information and technical expertise.
• Independently responsible for project science within his/her area of expertise on one or more project teams leading the extended characterization of complex biologic therapeutics.
• Develop, implement and execute novel analytical methods and techniques using
• Proactively seek out new information in the literature and incorporate this into individual projects as well as the overall program.
• Work in partnership with colleagues from Discovery, Process Chemistry/Engineering and Formulation Development departments, among others.
  
  
  

Qualifications

• Ph.D degree in Biochemistry, Analytical Chemistry, Pharmaceutical Sciences or a closely related discipline.
• Qualification for Senior Scientist I: 0-4 years of experience is required with relevant experience.
• Qualification for Senior Scientist II: 4 years of experience is required with relevant experience.
• Practical experience and strong knowledge in one or more of the following areas: protein/oligonucleotide HPLC, capillary electrophoresis, SPR, AF4, MALS, ELISA and/or mass spectrometry.
• Previous experience having maintained a laboratory notebook in compliance with Good Laboratory/Manufacturing Practices.
• Demonstrated record of independent thought, creativity and scientific accomplishment (e.g. peer reviewed journal publications, patents).
• Must possess a solid understanding of protein/oligonucleotide chemistry and biochemistry, particularly as related to biologics drug development.
• Strong data and time organization/management skills coupled with strong interpersonal and effective communication skills for facilitating collaborations with a demonstrated ability to lead cross functional process development teams.
• Effective writer and communication of research or other regulatory materials.
• Experience with the analysis of RNA, lipids, and lipid nanoparticles (LNPs) is a plus.
  
  
  

Leveling will be commensurate to experience.

Additional Information

Applicable only to applicants applying to a position in any location with pay disclosure requirements under state orlocal law:

• This is an on-site opportunity based out of AbbVie's Northern Chicago office.
• The compensation range described below is the range of possible base pay compensation that the Companybelieves ingood faith it will pay for this role at the timeof this posting based on the job grade for this position.Individualcompensation paid within this range will depend on many factors including geographic location, andwemay ultimatelypay more or less than the posted range. This range may be modified in thefuture.
• We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick),medical/dental/visioninsurance and 401(k) to eligibleemployees.
• This job is eligible to participate in our short-term incentiveprograms.
• This job is eligible to participate in our long-term incentiveprograms
  
  
  

Note: No amount of payis considered to bewages or compensation until such amount is earned, vested, anddeterminable.The amount and availability of any bonus,commission, incentive, benefits, or any other form ofcompensation and benefitsthat are allocable to a particular employee remains in the Company's sole andabsolutediscretion unless and until paid andmay be modified at the Companys sole and absolute discretion, consistent withapplicable law.

AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives, serving our community and embracing diversity and inclusion. It is AbbVies policy to employ qualified persons of the greatest ability without discrimination against any employee or applicant for employment because of race, color, religion, national origin, age, sex (including pregnancy), physical or mental disability, medical condition, genetic information, gender identity or expression, sexual orientation, marital status, status as a protected veteran, or any other legally protected group status.

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