Senior Scientist II, Biologics In Vitro Technologies

Company Description

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas immunology, oncology, neuroscience, and eye care and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us atwww.abbvie.com. Follow @abbvie onX,Facebook,Instagram,YouTube,LinkedInandTik Tok.

Job Description

The Biologics Discovery Sciences Group at AbbVie is seeking an accomplished scientist who will make substantial contributions to the conception, execution, and communication of antibody discovery strategies in a highly collaborative environment. A primary responsibility will be to develop and execute research strategies to enable the discovery and development of therapeutic antibodies for AbbVies core therapeutics areas. They will be responsible for the design and execution of in vitro display technologies for lead antibody identification/optimization. In addition, it is expected that the candidate will utilize their expertise to generate internal and external collaborations as necessary to further program goals. The successful candidate will be responsible for driving antibody discovery programs within a multidisciplinary research group in an exciting, fast-paced team environment.

Key Responsibilities

• Contribute to the conception, execution and communication of antibody discovery strategies in a highly collaborative environment.
• Develop and execute research strategies to enable the discovery and development of therapeutic antibodies and for AbbVies core therapeutics areas.
• Design and execution of in vitro display technologies for lead antibody identification/optimization and collaborating to generate stage-gate appropriate in vitro / cellular / in vivo data packages supporting PoC.
• Leverage expertise to develop and implement research to gain a detailed mechanistic understanding of the molecular pharmacology of therapeutic molecules.
• Ensure consistency and quality of technical reports.
• Provide project update, analysis and advice to cross-functional teams and senior management.
• Present original work internally across departments and at internal and external scientific conferences.
  
  
  

Qualifications

Qualifications:

• PhD, MS, or BS degree in Biochemistry, Biochemical engineering or related disciplines with typically 4 (PhD), 10 (MS), or 12 (BS) years of experience
• Hands-on experience with in vitro antibody discovery display technologies (e.g., phage, yeast, mammalian)
• Antibody/antibody fragment library design and construction
• Strong molecular biology skills
• Familiarity with sequence analysis tools (Geneious, Sequencher)
• Experience with flow cytometry
• Deep understanding of antibody structure and function
• Experience in antibody engineering and optimization (e.g., humanization, Fc optimization)
• Ability to explore and develop new approaches to further advance innovative biologics discovery
• Highly developed leadership and communication skills
• Keen ability to engage internal and external scientific leaders in collaborative research
• Excellent organization skills and the ability to manage multiple projects simultaneously
• Work in a collaborative environment with functional and therapeutic areas
• Adapt to rapid changes in project priorities and timelines
  
  
  

KeyAbbVie Competencies

• Builds strong relationships with peers and cross functionally with partners outside of the team to enable higher performance.
• Learns fast, grasps the essence and can change the course quickly where indicated.
• Raises the bar and is never satisfied with the status quo.
• Creates a learning environment, open to suggestions and experimentation for improvement.
• Embraces the ideas of others, nurtures innovation and manages innovation to reality.
  
  
  

Additional Information

Applicable only to applicants applying to a position in any location with pay disclosure requirements under state orlocal law:

• The compensation range described below is the range of possible base pay compensation that the Companybelieves ingood faith it will pay for this role at the timeof this posting based on the job grade for this position.Individualcompensation paid within this range will depend on many factors including geographic location, andwemay ultimatelypay more or less than the posted range. This range may be modified in thefuture.
• We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick),medical/dental/visioninsurance and 401(k) to eligibleemployees.
• This job is eligible to participate in our short-term incentiveprograms.
• This job is eligible to participate in our long-term incentiveprograms
  
  
  

Note: No amount of payis considered to bewages or compensation until such amount is earned, vested, anddeterminable.The amount and availability of any bonus,commission, incentive, benefits, or any other form ofcompensation and benefitsthat are allocable to a particular employee remains in the Company's sole andabsolutediscretion unless and until paid andmay be modified at the Companys sole and absolute discretion, consistent withapplicable law.

AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives, serving our community and embracing diversity and inclusion. It is AbbVies policy to employ qualified persons of the greatest ability without discrimination against any employee or applicant for employment because of race, color, religion, national origin, age, sex (including pregnancy), physical or mental disability, medical condition, genetic information, gender identity or expression, sexual orientation, marital status, status as a protected veteran, or any other legally protected group status.

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https://www.abbvie.com/join-us/reasonable-accommodations.html