Demo

Senior Scientist Upstream Processing

BioTalent
Oklahoma, OK Full Time
POSTED ON 3/7/2025
AVAILABLE BEFORE 4/5/2025

BioTalent are partnered with an expanding Biologics CDMO in Oklahoma to search for a Senior Scientist / Engineer to work on upstream process development as well as scale up and tech transfer projects.


As the Senior Scientist, you will lead multiple client projects across cell culture platforms working with media and bioprocess technologies for batch, fed-batch and perfusion systems. The projects will vary from bench scale (shake flasks and bench top high throughput bioreactors) through to pilot scale to support GMP-like processes.


You will be responsible for:

  • Leading multiple projects, overseeing internal project teams
  • Design, plan, and execute experimental protocols using shake-flasks, high throughput bioreactor systems (ambr15 / ambr250) and bench-top small scale bioreactors to optimize upstream cell culture process performance for manufacturing a variety of biologics such as monoclonal antibodies and therapeutic recombinant proteins.
  • Independently develop and optimize robust and scalable bioprocess platforms primarily fed-batch and perfusion systems.
  • Support Manufacturing groups by leveraging cell culture expertise to support investigations, troubleshooting complex technical challenges.
  • Specify and source new upstream equipment to expand the cell culture capabilities of the upstream development laboratory


You will bring the following:

  • PhD, Masters or Bachelor’s degree in Biochemical Engineering, Bioprocessing, Biotechnology or similar along with significant industry experience upstream processing for biopharmaceutical production.
  • Experience leading projects focused on mammalian cell culture processing, ideally at a variety of scales.
  • Experience with a variety of bioreactor systems will be highly desirable, Ambr15 and Ambr 250 experience is essential.


Apply now or reach out to greg.hammond@biotalent.com for more information!


BioTalent Ltd are acting as an employment agency in relation to this opportunity.

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