Associate Scientist II, Analytical Development, Viral Vector Product Development

This is what you will do:

This position will play a key role in Alexion’s Viral Vector Analytical Development team, interacting with internal teams within the Genomic Medicine and Product Development Clinical Supply teams. The research associate will follow established standard operating procedures (SOPs) to perform molecular and biochemical based assays to characterize recombinant adeno-associated viral (rAAV) vectors and other gene editing modalities to support process development and testing of pre-clinical grade research products.

You will be responsible for:

• Performing analysis of rAAV vectors (qPCR, ddPCR, ELISA, automated protein, and DNA electrophoresis)
• Independently conducting assays for in-process and final products to determine viral vector product quality
• Analyzing data and recording results in electronic lab notebook in a timely manner, writing reports, and communicating results to end users
• Assisting with vector reference qualification and development of existing assays for improved performance
• Writing technical reports and delivering scientific presentations summarizing data

You will need to have:

• BS in Cell Biology, Biochemistry, Molecular Biology, or related scientific discipline
• 2-4 years of relevant academic or industry experience
• Excellent attention to detail and accuracy in following protocols is necessary
• Must have strong organizational and communication skills
• Strong desire to learn multiple techniques and willingness to provide support as required
• Excellent interpersonal and collaborative skills, and the ability to work independently and effectively in a highly dynamic environment
• The duties of this role are generally conducted in an lab environment.  As is typical of a lab-based role, employees must be able, with or without an accommodation to: lift 15 pounds unassisted; work comfortably in a controlled environment with and around biological, infectious, and hazardous materials; gown/degown PPE; use a computer; engage in communications via phone, video, and electronic messaging; engage in problem solving and non-linear thought, analysis, and dialogue; collaborate with others; maintain general availability during standard business hours.

We would prefer for you to have:

• Experience testing AAV, viral vectors, or other types of biologics
• Experience with the performance of routine biological assays including qPCR, ddPCR, ELISA, SDS-PAGE, and agarose gel electrophoresis is desirable
• The ability and desire to learn new techniques if needed
• Candidates should be self-starters, comfortable with autonomy, and embrace opportunities to develop new genomic medicines as part of a dynamic team within Alexion.

Date Posted

31-Mar-2025

Closing Date

13-Apr-2025Alexion is proud to be an Equal Employment Opportunity and Affirmative Action employer. We are committed to fostering a culture of belonging where every single person can belong because of their uniqueness. The Company will not make decisions about employment, training, compensation, promotion, and other terms and conditions of employment based on race, color, religion, creed or lack thereof, sex, sexual orientation, age, ancestry, national origin, ethnicity, citizenship status, marital status, pregnancy, (including childbirth, breastfeeding, or related medical conditions), parental status (including adoption or surrogacy), military status, protected veteran status, disability, medical condition, gender identity or expression, genetic information, mental illness or other characteristics protected by law. Alexion provides reasonable accommodations to meet the needs of candidates and employees. To begin an interactive dialogue with Alexion regarding an accommodation, please contact accommodations@Alexion.com. Alexion participates in E-Verify.