Senior Scientist, Clinical Genomics and Molecular Assay Development

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POSITION

Senior Scientist , Clinical Genomics & Molecular Assay Development  

The clinical genomics Senior Scientist is responsible for developing molecular genomics biomarker strategies and implementing for programs across therapeutic areas. This includes but is not limited to responsibility for genomics and gene expression profiling (GEP) biomarker assay technology/ platform selection, evaluation of in-house or vendor choice per assay use requirements, development, optimization, qualification/validation and/or execution of biomarker analysis for BMS translational medicine and clinical programs. 

The scientist must have a strong technical background in PCR and NGS-based genomics and transcriptomics and its application in clinical programs, specific requirements are listed below:

Work onsite, maintaining a 100% laboratory-focused presence. Support multiple translational medicine and clinical projects simultaneously. Develop and execute genomic/transcriptomic strategies based on program and protocol requirements, including broad genomic profiling, pharmacodynamic, target engagement, predictive, and prognostic assays. Design, optimize, and execute biomarker assay protocols, including troubleshooting performance issues. Lead development, qualification, and validation of genomic assays (NGS or PCR-based) either internally or through external vendors. Evaluate and integrate emerging genomic technologies, performing feasibility assessments and pilot projects. Oversee assay development workflow and qualification/validation data generation and analysis, ensuring compliance with "fit-for-purpose" standards. Provide subject matter expertise and oversee outsourced assay development and clinical sample analysis, collaborating with Project Management teams. Draft and maintain detailed experimental documentation, including protocols, SOPs, and study summaries. Actively participate in internal and external collaborative teams and clinical biomarker execution teams. Interface closely with data analysis, sample management, and clinical operations teams. Mentor team members and promote efficient, streamlined genomics processes within the organization.

Minimum Requirements:

B.S with 13 years relevant experience, M.S. with 11 years relevant experience or 8 years Ph.D. in molecular biology, biochemistry, chemistry or a related life science.   Prior experience working in a CLIA-licensed lab would be a plus. The successful candidate must be capable of working and operating in a laboratory environment for the entirety of their work schedule. Significant experience and subject matter expertise in PCR, NGS or GEP application, significant technology and lab experience is a must.  The candidate must demonstrate significant work experience in clinical assay development for genomics assets preferably in a pharma, biotech, diagnostic or clinical lab setting. 

#LI-On-Site

If you come across a role that intrigues you but doesn’t perfectly line up with your resume, we encourage you to apply anyway. You could be one step away from work that will transform your life and career.

Uniquely Interesting Work, Life-changing Careers
With a single vision as inspiring as “Transforming patients’ lives through science™ ”, every BMS employee plays an integral role in work that goes far beyond ordinary. Each of us is empowered to apply our individual talents and unique perspectives in a supportive culture, promoting global participation in clinical trials, while our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.

On-site Protocol

BMS has an occupancy structure that determines where an employee is required to conduct their work. This structure includes site-essential, site-by-design, field-based and remote-by-design jobs. The occupancy type that you are assigned is determined by the nature and responsibilities of your role:

Site-essential roles require 100% of shifts onsite at your assigned facility. Site-by-design roles may be eligible for a hybrid work model with at least 50% onsite at your assigned facility. For these roles, onsite presence is considered an essential job function and is critical to collaboration, innovation, productivity, and a positive Company culture. For field-based and remote-by-design roles the ability to physically travel to visit customers, patients or business partners and to attend meetings on behalf of BMS as directed is an essential job function.

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