What are the responsibilities and job description for the Postdoctoral Associate - Infectious Disease and Microbiome Program (IDMP) position at Broad Institute of MIT and Harvard?
Job Description
We are seeking a postdoctoral researcher to join our group in the Laboratory of Michael Farzan. This position is based within the Infectious Disease and Microbiome Program (IDMP) at the Broad Institute, in affiliation with the Division of Infectious Diseases at Boston Children’s Hospital.
The postdoctoral researcher will lead the development of HIV-1 inhibitors using an in vivo evolution platform. The ideal candidate will have a strong background in molecular biology and immunology, with expertise in genome editing and next-generation sequencing (NGS) methods. The candidate should be highly motivated, capable of critical thinking, and eager to learn new techniques. Additionally, they should be proactive in leveraging the multidisciplinary network of scientists at the Broad Institute and engaging with fellow group members.
Key Responsibilities:
* Lead the development of protein biologics using an in vivo evolution platform.
* Establish pipelines for the generation and optimization of protein and mRNA vaccines.
* Conduct animal experiments to evaluate immune responses and optimize protein biologics.
* Apply advanced sequencing technologies to study antibody response and B cell biology.
* Perform efficient and reproducible analyses, ensuring rigorous quality control.
Requirements:
* PhD in biology, biochemistry, or a closely related field, with solid training in immunological methods.
* Computational/programming and analytical skills.
* Fast learner and analytical thinker, comfortable taking initiative to learn new skills and drive projects to completion.
* Demonstrated experience in biology and/or genetics, publication in scientific journals, and demonstrated ability to communicate scientific ideas through verbal presentations.
* Motivation to communicate research findings with the broader field through high-quality publications.
* Strong communication skills and willingness to engage with other members of the lab and contribute ideas through team meetings and discussions.
Overall Responsibilities
* Perform research utilizing tools and principles of cell and molecular biology to develop protein biologics.
* Make observations, analyze data and interpret results.
* Explore new biochemical and cell-based assays, methods, and technologies to advance project objectives. Provide training for graduate students and technicians. Work on problems in which analysis of data requires evaluation of identifiable factors.
* Exercise judgment within generally defined practices and policies in selecting methods and evaluation criteria for obtaining results.
Principle Duties
* In consultation with the supervisor, implement experiments to address specific questions defined by group projects.
* Make observations, analyze data and interpret results.
* Investigate and develop new methods and technologies for project advancement.
* Generate oral and written reports on performed experiments. Attend team meetings and present the results. May participate in scientific conferences and contribute to scientific journals.
* May contribute to the identification of patentable inventions.
* Consult with literature and scientific staff to maintain professional expertise.
* Work independently on routine work and receive instruction on new assignments.
Minimum Qualification
* Doctoral degree in life or chemical sciences required and relevant research experience in cell and molecular biology.
* Ability to exercise judgment within defined practices and techniques.
* Excellent communication skills and the ability to interact with all levels of staff and with external contacts.
* Exceptional organizational and critical thinking skills, lab notebook practices and attention to detail are essential.
We are seeking a postdoctoral researcher to join our group in the Laboratory of Michael Farzan. This position is based within the Infectious Disease and Microbiome Program (IDMP) at the Broad Institute, in affiliation with the Division of Infectious Diseases at Boston Children’s Hospital.
The postdoctoral researcher will lead the development of HIV-1 inhibitors using an in vivo evolution platform. The ideal candidate will have a strong background in molecular biology and immunology, with expertise in genome editing and next-generation sequencing (NGS) methods. The candidate should be highly motivated, capable of critical thinking, and eager to learn new techniques. Additionally, they should be proactive in leveraging the multidisciplinary network of scientists at the Broad Institute and engaging with fellow group members.
Key Responsibilities:
* Lead the development of protein biologics using an in vivo evolution platform.
* Establish pipelines for the generation and optimization of protein and mRNA vaccines.
* Conduct animal experiments to evaluate immune responses and optimize protein biologics.
* Apply advanced sequencing technologies to study antibody response and B cell biology.
* Perform efficient and reproducible analyses, ensuring rigorous quality control.
Requirements:
* PhD in biology, biochemistry, or a closely related field, with solid training in immunological methods.
* Computational/programming and analytical skills.
* Fast learner and analytical thinker, comfortable taking initiative to learn new skills and drive projects to completion.
* Demonstrated experience in biology and/or genetics, publication in scientific journals, and demonstrated ability to communicate scientific ideas through verbal presentations.
* Motivation to communicate research findings with the broader field through high-quality publications.
* Strong communication skills and willingness to engage with other members of the lab and contribute ideas through team meetings and discussions.
Overall Responsibilities
* Perform research utilizing tools and principles of cell and molecular biology to develop protein biologics.
* Make observations, analyze data and interpret results.
* Explore new biochemical and cell-based assays, methods, and technologies to advance project objectives. Provide training for graduate students and technicians. Work on problems in which analysis of data requires evaluation of identifiable factors.
* Exercise judgment within generally defined practices and policies in selecting methods and evaluation criteria for obtaining results.
Principle Duties
* In consultation with the supervisor, implement experiments to address specific questions defined by group projects.
* Make observations, analyze data and interpret results.
* Investigate and develop new methods and technologies for project advancement.
* Generate oral and written reports on performed experiments. Attend team meetings and present the results. May participate in scientific conferences and contribute to scientific journals.
* May contribute to the identification of patentable inventions.
* Consult with literature and scientific staff to maintain professional expertise.
* Work independently on routine work and receive instruction on new assignments.
Minimum Qualification
* Doctoral degree in life or chemical sciences required and relevant research experience in cell and molecular biology.
* Ability to exercise judgment within defined practices and techniques.
* Excellent communication skills and the ability to interact with all levels of staff and with external contacts.
* Exceptional organizational and critical thinking skills, lab notebook practices and attention to detail are essential.
