Postdoctoral Researcher - Newman lab (clinical)

Position Summary
The Newman Lab studies how signaling metabolites regulate aging mechanisms and applies these insights to address key clinical challenges. We seek a motivated and creative scientist to lead projects spanning biochemistry to translational applications in a dynamic and collaborative environment, under the mentorship of a physician-scientist. This is a 100% on-site position.

Position Description
We are engaged in multiple projects exploring aging biology within biospecimen-rich clinical trials and cohorts. Our objectives include:

• Evaluating biological proof-of-concept for interventions, such as ketone esters, that may modulate aging mechanisms.
• Analyzing biomarkers of aging in clinical cohorts with accelerated aging conditions.
• Investigating the role of aging biology in geriatric syndromes.

The selected candidate will take on an operational leadership role in an ongoing or new geroscience clinical study. Responsibilities include managing day-to-day study activities, leading data and biospecimen analyses, and contributing to grant writing and scientific publications.

This role involves:

• Biospecimen processing and analysis.
• Bioinformatic analysis of complex multi-omic datasets.
• Close collaboration with bench scientists, core facilities, and external clinical research partners.

This position provides training opportunities to develop expertise in translational research, preparing the candidate for a career in this field.

Qualifications

• MD and/or PhD in Epidemiology, Clinical Research, Translational Science, or a related field.
• Strong communication skills and ability to thrive in collaborative team environments.
• Proven ability to independently manage a research project.
• Self-motivated with a passion for continuous learning and skill development.
• Extensive experience in clinical research, including study design, regulatory approvals, participant visits, and logistics management.
• Basic bench laboratory skills, including:
  • DNA, RNA, and protein isolation
  • PCR, Western blotting, electrophoresis
• Prior coding or bioinformatics experience is a plus.
• Deep interest in aging science and translational interventions aimed at extending human healthspan.
• Strong aptitude for technology, translational medicine, and knowledge transfer.
• Ability to process, curate, and integrate in-house and public domain datasets.
• Experience in scientific writing, including research grants and publications.
• Bilingual in Spanish is a plus

Compensation & Benefits

• Opportunity to work in a cutting-edge, collaborative research environment using state-of-the-art techniques.
• Competitive 2025 salary: Starting at $71,845 - $80,000, commensurate with experience.
• Generous benefits package, including:
  • Health insurance
  • Paid parental leave
  • Vacation & sick leave
  • 401(k) with 5% employer match and student loan option
• Visa sponsorship is not available. Applicants must be a U.S. citizen or green card holder.
• Candidates must reside within a reasonable commuting distance on their first day of work.

About the Buck Institute
At the Buck Institute, we are redefining healthcare by tackling the fundamental mechanisms of aging. Our mission is to extend human healthspan by assembling the best and brightest scientists across disciplines to combat age-related diseases, including Alzheimer’s, Parkinson’s, cancer, heart disease, and diabetes. Located in Marin County, CA, we are a globally recognized, independent, non-profit research institution dedicated to pioneering aging science. 

How to Apply
To apply, please submit the following documents online:

1. Curriculum Vitae (CV)
2. Brief statement of research interests and goals
3. Contact information for 2-3 references familiar with your scientific work
4. Letter of support from your PhD or prior postdoctoral adviser

For more information, contact Thelma García, PhD at tgarcia@buckinstitute.org.

 

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