What are the responsibilities and job description for the ASSOCIATE DIRECTOR/DIRECTOR- BIOLOGICS position at Calibr?
ABOUT US:
Calibr-Skaggs Institute for Innovative Medicines was founded on the principle that the creation of new medicines can be accelerated by pairing world-class biomedical research with state-of-the-art drug discovery and development capabilities. Calibr-Skaggs is a division of Scripps Research, a first-of-its-kind, nonprofit translational research institute dedicated to creating the next generation of medicines. Scripps Research is ranked the most influential institution in the world for its impact on innovation. Our educational and training programs mold talented and committed students and postdocs into leading-edge scientists. Leveraging the unique scientific environment of Scripps Research, impacting translational sciences, Calibr-Skaggs has created a portfolio of drug candidates, and is shaping a new paradigm for advancing nonprofit biomedical research to impact patients while reinvesting in further innovative research. We expand basic knowledge in the biosciences and use these fundamental advancements to develop profound innovations that improve wellbeing. Calibr-Skaggs’ drug development portfolio spans a broad range of human diseases, including cancer, autoimmunity and inflammatory diseases, metabolic and cardiovascular diseases, infectious and neglected tropical diseases, as well as age-related and degenerative diseases. If you have a passion for making a difference, this is your opportunity to join our transformative team.
POSITION TITLE: Associate Director/ Director Biologics
POSITION SUMMARY:
Calibr-Skaggs is seeking exceptional candidates for the role of Associate Director or Director on our Biologics team who will help translate potentially transformative therapies into first-in-human clinical studies—a critical step to bringing new medicines to patients. Specifically, this position will be responsible for the development of a portfolio of biologics programs focused on immunology and oncology from concept to IND submission. Modalities of focus include monoclonal antibodies, Mult specific antibodies, antibody-drug conjugates, fusion proteins, and enzymes. The Associate Director will lead these programs in partnership with the protein sciences team and will work closely with our highly experienced translational team including pharmacology, toxicology, CMC (chemistry, manufacturing, and controls), and clinical groups. This Associate Director or Director will also work closely with other internal and external stakeholders to critically evaluate data, present programs, and review new opportunities. In addition, the Associate Director will have the opportunity to engage with other teams at Calibr-Skaggs including medicinal chemistry and cell biology groups to collaborate on a wide range of programs in infectious and neglected tropical diseases, metabolic disorders, neurological conditions, and other rare disease indications. Endless opportunities await those who join our team.
The Associate Director will serve an integral role in Calibr-Skaggs’ highly engaging and collaborative ecosystem developed within Scripps Research Institute and will be encouraged to engage in the seamless flow of ideas within and between the institutes. The ideal candidate is expected to bring with them the proficiencies listed below and can expect to receive world-class training in translational medicine at Calibr-Skaggs. Candidates with experience in antibody engineering, drug discovery, assay development, and in vivo models who are looking to take the next steps in their career and join a high-impact team are encouraged to apply. This position offers significant growth opportunity through promotion structures designed to retain exceptional talent within the Calibr-Skaggs team.
DUTIES & RESPOSNSIBILITIES:
- Manage and lead a portfolio of biologics programs
- Design, generate, and develop antibody-based programs
- Evaluate, initiate, and develop projects through IND-enabling studies
- Review, prepare, analyze, interpret, and present data to key stakeholders
- Evaluate and stay on top of competitive landscape to strategically position programs for success
- Critically evaluate new opportunities to initiate new programs
- Author manuscripts and poster presentations to disseminate publicly
- Author relevant IND sections for late-stage programs
- Maintain budgets and timelines for programs within the portfolio
- Manage FTE effort across programs within the portfolio
KEY COMPETENCIES:
- Excellent verbal, written, and interpersonal communication skills – including proficiency in scientific terminology and writing skills
- Experience in antibody discovery research is important
- Exceptional data analysis abilities, and proficiency with relevant software is expected
- Good understanding of statistical principles and methods
- Experience with GLP/GMP is helpful but not required
- Adaptable / Flexible - willing and able to adjust to multiple demands and shift priorities as well as an ability to meet day-to-day challenges with confidence and professionalism
- Proficient critical thinking, problem-solving, decision-making skills and an exceptional commitment to quality
REQUIRED QUALIFICATIONS:
- Master’s degree with 10 years’ experience or PhD with 6 years’ experience in industry
- Must have industry experience in drug development / drug discovery
PHYSICAL REQUIREMENTS:
This position works in a laboratory environment. Further details of the physical requirements of established essential functions for this position will be addressed/discussed during the interview process.
COMPENSATION:
The expected hiring range for this multi-level position is $125,000 - $223,200 per year, commensurate with experience. Consideration will be given to experience that exceeds the listed requirements.
COMPREHENSIVE BENEFITS INCLUDE:
- Eligibility for retirement plans with employer contribution.
- Full suite of Health and Welfare plans including three medical plan options (including an HSA available option), dental, vision, life insurance, disability, EAP and more.
- Access to Flexible Spending Accounts (Medical/Dependent Care).
- Competitive vacation and sick leave policies.
- Free, on-site Counseling Center which provides confidential counseling services to benefits-eligible employees and their family members.
- Free, on-site parking.
The above statements describe the level of work performed and expected in general terms. The statements are not intended to list all the responsibilities, duties and/or skills required of employees so classified, and the content herein is subject to change due to the business needs of Scripps Research, with or without notice. Furthermore, nothing in this job description shall be interpreted to be in conflict with or to eliminate or modify in any way the employment-at-will status of Scripps Research staff.
EEO Statement:
The Scripps Research Institute is an Equal Opportunity Employer. We promote diversity of thought, culture and background in the fields of science. All qualified applicants are encouraged to apply and will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, protected veteran status, or any other legally protected characteristic or status.
Salary : $125,000 - $223,200
