What are the responsibilities and job description for the Dir - Neurology Business Grp position at Clark Davis Associates, Inc?
Bergen County, NJ - Pharmaceutical & Biotech - Remote - Full time
Date Posted : 2 / 24 / 2025
Director, Pharmacometrics, Clinical Pharmacology and Translational Medicine - Neurology Business Group
Bergen County, NJ (Remote)
Searching for a creative, resourceful, integrative thinker who is driven to use cutting edge modeling approaches to advance the clinical and translational research in Neuroscience Business Group. This individual will provide scientific leadership to develop and execute impactful pharmacometric strategies in support of key decisions for programs across all phases of drug development. The complexity and scale of data being generated has grown significantly and requires strong scientific contributions to integrate different approaches in modeling, statistics and data science to bring value to the company’s portfolio. This role requires diverse modeling experience in drug development within pharma / biotech, agility in being able to handle both hands-on modeling and strategic leadership for a dynamic project portfolio and a strong track-record of scientific and collaborative leadership in complex projects and initiatives.
Essential Functions :
- In-depth modeling skills, ability to translate complex problems into incisive models.
- Develop and execute population PK, exposure response, mechanistic PK / PD models of neurodegenerative diseases, including physiologically-based pharmacokinetic (PBPK), quantitative system pharmacology (QSP) models, clinical trial simulations, literature meta-analysis, machine-learning / deep learning and other state of the art quantitative techniques.
- Leverage pharmacometrics to make impactful contributions in drug development decision-making and regulatory submissions.
- Represent Pharmacometrics and effectively communicate pharmacometric input to key management and decision boards.
- Develop pharmacometrics strategies for Translational Medicine (in particular using continuous, longitudinal biomarkers) and various big, digital, historical data groups and initiatives.
Qualifications :
PhD or PharmD in Pharmaceutical Sciences, Clinical Pharmacology, Applied Mathematics, Engineering or related area with strong background in the application of mathematical and statistical methods with 7 years of experience. Proficiency in Non-linear mixed effects (NLME), mechanistic modeling approaches and using NONMEM, Monolix, R, Matlab or other modeling software. Proficiency in written and verbal communication, interdisciplinary collaboration, and problem scoping and planning. Experience and disease knowledge in neuroscience is preferable.
Please contact Darren Gutowski at dgutowski@clarkdavis.com
J-18808-Ljbffr
