Postdoctoral Fellow - Chaitali Ghosh Lab

At Cleveland Clinic Health System, we believe in a better future for healthcare. And each of us is responsible for honoring our commitment to excellence, pushing the boundaries and transforming the patient experience, every day. We all have the power to help, heal and change lives — beginning with our own. That’s the power of the Cleveland Clinic Health System team, and The Power of Every One. Job Title Postdoctoral Fellow - Chaitali Ghosh Lab Location Cleveland Facility Cleveland Clinic Main Campus Department Job Code X1004 Shift Variable Schedule 12:00am-12:00am Job Summary Highly motivated individuals with a PhD or MD/PhD in relevant area are encouraged to apply. This training position, under the direct supervision of a Cleveland Clinic Principal Investigator will provide practical training and experience in a research setting. This position is appointed through the Lerner Research Institute. The successful applicant will be able to demonstrate a commitment to research, a collaborative work ethic and strong communication skills, both written and verbal. This program is expected to be completed within 5 years. Job Details The Chaitali Ghosh lab in the Department of Biomedical Engineering, Lerner Research Institute at Cleveland Clinic, Cleveland, OH is recruiting an enthusiastic and motivated postdoctoral research fellow to join on a project focusing on the Molecular Mechanism of Glucocorticoid Receptor, Cytochrome P450, and P-Glycoprotein Axis on Drug Regulation at the Blood-Brain Barrier in Epilepsy. The Ghosh laboratory is engaging in multi-disciplinary research projects in blood-brain barrier and epilepsy research by collaborating with basic and clinical researchers from Lerner Research Institute and the Neurological Institutes at Cleveland Clinic. A successful postdoctoral candidate should have a PhD in the relevant field with a strong background in basic science, molecular biology, blood-brain barrier research, rodent seizure/epilepsy models and neuroscience. The candidate should be well-versed with basic neurobiology, molecular biology, cell culture techniques, rodent electrode implantation surgery and recording of brain activity. Applicant should be able to demonstrate a commitment to research, a collaborative work ethic and strong communication skills, both written and verbal. Highly motivated individuals with a PhD or MD/PhD in relevant area are encouraged to apply. Job Responsibilities includes independent project design with the goal of data generation, analysis, interpretation and manuscript preparation; perform experiments and make new discoveries; present data for manuscripts and conferences; procure independent funding to support research and train junior personnel. Principal Investigator: Chaitali Ghosh, PhD Lerner Research Institute Department: Biomedical Engineering Lab Research Topics: Blood-brain barrier Epilepsy and epilepsy with other comorbidities Cellular and Molecular Neurobiology Pharmacokinetics and Pharmacodynamics Epigenetics and biomarkers For more information about the lab’s research, please visit: https://www.lerner.ccf.org/biomedical-engineering/ghosh/ or contact Dr. Chaitali Ghosh at ghoshc@ccf.org. Job Responsibilities: Independent project design with the goal of data generation, analysis, interpretation and manuscript preparation Perform experiments independently Ability to design projects, generate, analyse and intergrate data for presentations and manuscript Procure independent funding to support research Rodent brain surgeries, electrode implantation & recording Education: PhD or MD/PhD required MD with relevant laboratory experience may substitute for PhD Languages: English Proficiency proof required for candidates arriving on J-1, J-2, or F1 OPT visa status Work Experience: Previous experience in a research or academic setting. Graduate student experience meets this requirement. Scientific writing experience Additional Preferred Qualities: Passionate towards research and new discoveries Good communication skills and hardworking ethics Collegial and excellent team player Demonstrate good scientific writing skills and knowledge in basic research Ability to operate lab equipment's and computer software's for analysis Physical Requirements: Ability to perform work in a stationary position for extended periods Ability to operate a computer and other office equipment Ability to communicate and exchange accurate information Ability to distinguish color Manual dexterity to handle specimens and repair equipment Ability to lift and transport equipment or specimens weighing up to 20 pounds May be exposed to hazardous chemicals, bio-hazards, radioactive materials, etc. Personal Protective Equipment: PPE per institutional requirements; may vary by laboratory Preferred Application Materials: CV or NIH format Biosketch, Statement of research accomplishments (1-page) Names of 3 Referees All application materials should be submitted directly via email to Chaitali Ghosh at ghoshc@ccf.org. Keywords: Postdoc, Research, LRI, Lerner Research Institute, Research fellow, Cleveland Clinic, In vitro and In vivo Blood-brain barrier models, Rodent Brain surgery, Epilepsy Research, Blood-brain barrier Research, Rat and mouse models, Immunohistochemistry, Western Blotting, High Performance Liquid Chromatography/Mass Spectrometry, RT-PCR, Epigenetic, DNA methylation, ELISA, Primary cell cultures, Neurovascular Unit, Molecular Neurobiology, Biomarkers The policy of Cleveland Clinic Health System and its system hospitals (Cleveland Clinic Health System) is to provide equal opportunity to all of our caregivers and applicants for employment in our tobacco free and drug free environment. All offers of employment are followed by testing for controlled substance and nicotine. All offers of employment are follwed by testing for controlled substances and nicotine. All new caregivers must clear a nicotine test within their 90-day new hire period. Candidates for employment who are impacted by Cleveland Clinic Health System's Smoking Policy will be permitted to reapply for open positions after one year. Cleveland Clinic Health System administers an influenza prevention program. You will be required to comply with this program, which will include obtaining an influenza vaccination on an annual basis or obtaining an approved exemption. Decisions concerning employment, transfers and promotions are made upon the basis of the best qualified candidate without regard to color, race, religion, national origin, age, sex, sexual orientation, marital status, ancestry, status as a disabled or Vietnam era veteran or any other characteristic protected by law. Information provided on this application may be shared with any Cleveland Clinic Health System facility. Please review the Equal Employment Opportunity poster. Cleveland Clinic Health System is pleased to be an equal employment employer: Women / Minorities / Veterans / Individuals with Disabilities We know that fully supporting our caregivers is what creates the best outcomes for our patients. Our outstanding, comprehensive offerings are an investment in your health, well-being and future. What began in Cleveland in 1921 has grown to include locations throughout, the U.S. and even other countries. For you, that means more opportunities to learn, grow and serve patients — while finding caring, thriving communities both at work and at home. Cleveland Clinic is a nonprofit multispecialty academic medical center that integrates clinical and hospital care with research and education. Headquartered in Cleveland, Ohio, it was founded in 1921 by four renowned physicians with a vision of providing outstanding patient care based upon the principles of cooperation, compassion and innovation. Cleveland Clinic has pioneered many medical breakthroughs, including coronary artery bypass surgery and the first face transplant in the United States. U.S. News & World Report consistently names Cleveland Clinic as one of the nation’s best hospitals in its annual “America’s Best Hospitals” survey. Among Cleveland Clinic’s 70,800 employees worldwide represent 140 medical specialties and subspecialties. Cleveland Clinic is a 6,500-bed health system that includes a 173-acre main campus near downtown Cleveland, 19 hospitals, more than 220 outpatient facilities, and locations in southeast Florida; Las Vegas, Nevada; Toronto, Canada; Abu Dhabi, UAE; and London, England.