What are the responsibilities and job description for the Bioconjugation (ADC) Process Development Scientist (Contract) position at Connect Life Sciences?
Job Duties :
- Technical knowledge at design, execution and data interpretation of experiments related to development, optimization, and scale-up of biologics with a focus on ADC BioConjugation and Purification processes.
- Develop Subject Matter Expertise in bioconjugation (ADC) process development and manufacturing in support of CMC activities.
- Work closely with research function to understand relevant conjugation chemistries and transition bioconjugation process from research to CMC development.
- The ability to identify, evaluate, and implement new and existing technologies to improve process efficiency, control, and understanding.
- Experience in applying DOE and other advanced statistical techniques to design experiments (DoE) related to process development.
- Familiarity with authoring high-quality documents, including technical reports, SOPs, experimental protocols, drafting tech transfer related documents (process description, process flow diagrams, tech transfer reports, etc.), reviewing batch records, and sampling plans.
- The ability to contribute to MFG floor activities and provide scale up, technical support and troubleshooting to MFG groups at clinical and commercial manufacturing sites.
- Demonstrated ability to work effectively with CDMOs, is a plus.
- A familiarity with critically relevant areas such as analytical, formulation, and the general CMC scope for biologics is preferred.
Requirements :
