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Senior Associate Scientist

Connecticut Innovations
New Haven, CT Full Time
POSTED ON 4/13/2025
AVAILABLE BEFORE 5/11/2025

Are you ready to join Connecticut Innovation’s vibrant community of innovators? Connecticut Innovations (“CI”) is Connecticut’s strategic venture capital arm, and we are passionate about serving our portfolio of 220 companies across various industries, with strengths in life sciences, technology, and climate tech.

Come join Taking Hold. Conquering Cancer. - Halda TherapeuticsHalda Therapeutics as Associate Scientist / Senior Associate Scientist!

Halda Therapeutics

Halda Therapeutics is a New Haven CT based, venture-backed biotechnology company focused on the development of a proprietary RIPTAC™ (Regulated Induced Proximity TArgeting Chimeras) therapeutic that works by a novel “hold and kill” mechanism for the precision treatment of cancer. The mechanism of action of RIPTAC therapeutics is uniquely designed to address cancer’s ability to evolve bypass mechanisms of resistance, a common limitation of today’s precision oncology medicines.

Our lead RIPTAC programs are in development for major solid tumor types, prostate cancer and breast cancer, with additional RIPTAC therapeutic programs in our pipeline to treat unmet medical needs in cancer. The company will initiate its Phase 1 trial in metastatic, castration-resistant prostate cancer (mCRPC) in 2025. Halda was founded by Yale Professor Craig Crews and is led by a team with deep expertise in bifunctional drug discovery, platform innovation, and company building and is located in New Haven, CT. The company has raised $202M in funding from top tier investors, and closed on $126M in the summer of 2024 to bring its first two programs into the clinic.

At Halda, our team is a collective force for drug innovation to conquer cancer. Halda is a place where you can embrace your purpose and be your true self. Learn more about us at .

Associate Scientist / Senior Associate Scientist - Biology | Position Overview

We are looking for a scientist with a foundation in cell biology to support hit identification and lead optimization efforts as part of the Exploratory Projects Team. Halda is seeking a candidate with a background in cell or molecular biology, including previous experience with mammalian cell culture and the development and execution of cell-based assays. The candidate will be responsible for conducting assays designed to evaluate molecular interactions as well as interrogate aspects of oncogenic signaling. The candidate would be expected to directly support early pipeline biology efforts on novel RIPTAC programs through a combination of benchwork, data analysis and organization, and presentation for the scientific and management teams.

Qualifications

Associate scientist :

  • M.S. in cell / molecular biology or a related field with 2 years of work experience, or
  • B.S. in cell / molecular biology or a related field with 4 years of work experience.

Senior associate scientist :

  • M.S. in cell / molecular biology or a related field with 4 years of work experience, or
  • B.S. in cell / molecular biology or a related field with 6 years of work experience.
  • Ability and desire to support early discovery projects through lead optimization and beyond.
  • Experience with standard analytical techniques such as immunoblotting, ELISA, qPCR, cell viability etc.
  • Hands-on experience in aseptic cell culture technique.
  • Hands-on experience developing and executing cell-based assays.
  • Ability to design and execute experiments that answer specific scientific questions.
  • Ability to communicate experimental results and interpretation to the rest of the scientific team.
  • An ideal candidate will also have :

  • Experience engineering cell lines to overexpress, mutate, knock down, and knock out genes of interest.
  • Experience using liquid-handling equipment for assay automation.
  • Excellent interpersonal, communication, organizational, teamwork, and planning skills to accomplish multiple tasks and meet deadlines in a timely manner.
  • Ability to function within a multi-disciplinary team of cell biologists, chemists, structural biologists, and biochemists to advance small-molecule drug discovery projects.
  • Compensation

    The estimated salary range for this position is $78,000-105,000. Actual compensation will be dependent on candidate experience and other factors. The compensation will also include an annual bonus and equity.

    Benefits

    Halda offers a competitive benefit package, including subsidized medical, dental, vision, ST / LT disability, a 401k Plan with generous company contribution and free parking at our New Haven headquarters. We also offer tuition reimbursement and paid parental leave.

    This role is located in New Haven, CT and relocation is not available for this role. Halda is an Equal Opportunity Employer.

    Salary : $78,000 - $105,000

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