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Bioprocess Engineer

DATALYTICA LLC
Arlington, VA Full Time
POSTED ON 1/17/2025
AVAILABLE BEFORE 4/15/2025

Job Description

Job Description

Benefits :

  • 401(k) matching
  • Dental insurance
  • Health insurance
  • Paid time off
  • Tuition assistance

Datalytica has an immediate opening in Arlington, VA for an onsite Bioprocess Engineer to support the Biological Technologies Office (BTO) at DARPA. The ideal candidate will have a PhD in Chemical Engineering, Bioprocessing Engineering or related degree and an active DoD Secret Clearance with the ability to obtain a TS / SCI.

Job Overview

This is an exciting opportunity involving innovative bioprocess scaling and engineering that transform how biological production systems are designed, optimized and scaled.

The role of this key position is to collaborate with the Program Managers and cross-functional teams as you apply first principle thinking, bridge theoretical understanding with practical implementation, balance cellular requirements with engineering constraints all while identifying and resolving scale-dependent process challenges.

If this sounds like a normal day for you, then keep reading!

Key Responsibilities

  • Provide expert technical support to Program Managers (PMs) in developing and refining revolutionary bioprocess engineering concepts.
  • Develop and contribute to Program Initiation Pitches (PIPs) through collaboration with PMs and System Engineer Technical Assistant (SETA) teams, ensuring alignment with leadership feedback.
  • Scale biological processes from bench (0.5-5L) through pilot scale (50-500L), including process characterization, media / feed strategy optimization, and validation of scale-down models.
  • Stay current with emerging bioprocess technologies and strategies, including process intensification, real-time process analytical technologies (PAT), and continuous processing.
  • Conduct analytical assessments of fundamental research to support PM decision-making and identify potential technical opportunities and risks.
  • Interface with key opinion leaders across academia, industry, and government to gather insights for program development.
  • Perform initial technoeconomic analyses of novel processes to ensure feasibility and effectiveness.
  • Effectively communicate complex engineering concepts to diverse audiences, including technical and non-technical stakeholders.
  • Minimum Qualifications

  • Advanced degree (preferably a PhD) in Chemical Engineering, Bioprocess Engineering, or a related field with a strong focus on biological systems.
  • Active Secret Security Clearance or higher with the ability to obtain a TS / SCI.
  • 2 years experience scaling biological processes bench through pilot scale.
  • Hands on Knowledge with the following :
  • Process Modeling and Simulation Software - SuperPro Designer, Aspen

  • Flux Balance Analysis Metabolic modeling
  • Statistical Design of Experiments and Process Control using JMP or R with Minitab
  • Process Analytical Technology implementation
  • CFD for bioreactor characterization
  • Experience with multiple cell lines (bacterial, yeast, mammalian) and various bioreactor types (STR, airlift, perfusion / HF).
  • Desired Qualifications

  • Familiarity with advanced process development strategies such as high-throughput screening and scale-down models.
  • Understanding of common scale-up challenges, including oxygen transfer limitations, shear effects, and cell line stability.
  • Strong interdisciplinary collaboration skills with the ability to work across scientific and engineering domains.
  • Datalytica Benefits

    At Datalytica, we pride ourselves on being a dynamic and innovative small business with three core divisions that allow us to deliver exceptional value to our clients.

  • Our Product Division specializes in AI and cybersecurity products, focusing on cutting-edge capabilities like AI black-box reverse engineering, 5G red team development, and critical event detection.
  • Our Service Division provides Systems, Engineering, and Technical Assistance (SETA) to government agencies, including DARPA, ARPA-H, DTRA, and NSA, offering essential technical, management, financial, and administrative support.
  • Our Training and Outreach Division is dedicated to delivering advanced technical education, including certifications in AI, cybersecurity, data science, and digital technologies, while fostering collaboration across academia, government, and industry.
  • For our employees we offer a comprehensive benefits package that supports both your professional and personal well-being. Join our team in its contribution and support of our nations security mission while benefiting from the following :

  • 401(k) Match
  • Excellent Health Benefits
  • Tuition Reimbursement
  • Work / Life Balance
  • Equal Employment Opportunity

    Datalytica is an Equal Opportunity Employer. Employment decisions are made without regard to race, color, religion, national or ethnic origin, gender, sexual orientation, gender identity or expression, age, pregnancy, disability, genetic factors, protected veteran status, or other characteristics protected by law.

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