Demo

Computational Chemist

Debut
San Diego, CA Full Time
POSTED ON 4/19/2025
AVAILABLE BEFORE 5/18/2025
About Debut

Debut is the unconventional innovation lab spearheading the next generation of big business. Only Debut has a scalable, integrated, climate-positive creation model powered by biotechnology that puts human wellbeing at the center of everything we do—setting the new standard for profitable business and a new pace for an ever-changing world. Our hybrid biotechnology approaches unlock latent markets, providing access to sustainably produced, natural ingredients with health benefits that cannot be obtained through other methods. We are committed to traversing the entire process, from ingredient discovery to the scaling of these products, for consumer markets. If you are passionate, enjoy fast-paced innovation and collaborative teams, then Debut is for you. 

Computational Chemist

Location: San Diego, CA (Onsite full-time required)

Summary

We are seeking a highly motivated and skilled Computational Chemist to join Debut. As a member of the Ingredient Innovation team, you will work with large-scale biological and chemical datasets to design and optimize novel active ingredients for consumer products. The ideal candidate will have proven experience in developing custom predictive and generative machine learning models. This highly collaborative position will involve close interaction with team members specializing in next-generation sequencing (NGS), chemistry, bioinformatics, AI/ML, and product development to bring innovative, scientifically backed ingredients to the market.

Essential Functions

  • Develop and implement ML tools and workflows to discover molecules with desired biological and chemical properties
  • Prepare and analyze large-scale, high-dimensional datasets for training QSAR/ML models
  • Explore diverse generative ML algorithms to design novel bioactive molecules
  • Optimize computational workflows for efficiency and develop new data visualizations to generate insights
  • Apply cheminformatics expertise to support project team in data interpretation and decision-making



Education and Experience

  • BS, MS, or PhD degree in Computational Chemistry, Cheminformatics, Bioinformatics, or a related STEM field
  • 3 years of practical experience in cheminformatics, either in academia or industry
  • Strong proficiency in Python, including libraries such as RDKit, Scikit-learn, Tensorflow, PyTorch, Pandas, and Matplotlib. Experience with R is a plus
  • Familiarity with Linux-based environments, bash scripting, Conda, and Git
  • Experience working with medicinal chemistry or genomics data is preferred
  • Excellent problem-solving and communication skills, with demonstrated ability to work independently and collaboratively with both internal and external teams



Essential Physical Characteristics

The physical characteristics described here are representative of those that must be met by an employee to successfully perform the essential functions of this position. Reasonable accommodations may be made to enable qualified individuals with disabilities to perform the essential functions of a job, on a case-by-case basis.

  • Continuous upward and downward flexion of the neck.
  • Frequent: sitting, repetitive use of hands to operate computers, printers and copiers.
  • Frequently uses hands to feel objects or control tools (e.g. pipetting). Laboratory operations require dexterity and care to perform studies as required.
  • Occasional: walking, standing, climbing stairs, bending and twisting of neck, bending and twisting of waist, squatting, simple grasping, reaching above and below shoulder level, and occasional lifting and carrying of files or material weighing up to 50 pounds.
  • Must be willing to work with biohazardous agents (up to BSL2).
  • The R&D laboratory will result in exposure to hot and cold temperatures, noise, fumes, limited dust, and oily coolants.
  • The performance of this position will present exposure to an industrial environment and requires support and compliance with the published Company PPE policy including but not limited to the use of personal protective equipment such as safety glasses with side shields, appropriate attire, safety shoes, hard hat, hearing protection, etc.

Condition of Employment

As part of Debut's pre-employment process, prospective candidates will undergo a background check prior to beginning employment. Additional types of background investigations may be conducted based on the job-related activities of the position.

Debut is an equal opportunity employer. All applicants will be considered for employment without attention to race, color, religion, sex, sexual orientation, gender identity, national origin, veteran, or disability status.

Salary: $80,000 - $100,000 per year

Salary : $80,000 - $100,000

If your compensation planning software is too rigid to deploy winning incentive strategies, it’s time to find an adaptable solution. Compensation Planning
Enhance your organization's compensation strategy with salary data sets that HR and team managers can use to pay your staff right. Surveys & Data Sets

What is the career path for a Computational Chemist?

Sign up to receive alerts about other jobs on the Computational Chemist career path by checking the boxes next to the positions that interest you.
Income Estimation: 
$99,598 - $128,732
Income Estimation: 
$101,850 - $147,372
Income Estimation: 
$82,394 - $101,811
Income Estimation: 
$86,266 - $138,642
Income Estimation: 
$128,588 - $163,256
Income Estimation: 
$77,423 - $102,547
Income Estimation: 
$74,048 - $101,143
Income Estimation: 
$70,620 - $94,639
Income Estimation: 
$91,114 - $126,315
Income Estimation: 
$99,598 - $128,732
Income Estimation: 
$99,598 - $128,732
Income Estimation: 
$101,850 - $147,372
Income Estimation: 
$82,394 - $101,811
Income Estimation: 
$86,266 - $138,642
Income Estimation: 
$128,588 - $163,256
Income Estimation: 
$128,588 - $163,256
Income Estimation: 
$111,881 - $143,704
Income Estimation: 
$95,921 - $146,578
Income Estimation: 
$133,838 - $172,011
Income Estimation: 
$136,751 - $179,120
Income Estimation: 
$64,157 - $83,937
Income Estimation: 
$52,659 - $76,910
Income Estimation: 
$60,357 - $79,610
Income Estimation: 
$61,862 - $86,380
Income Estimation: 
$91,114 - $126,315
View Core, Job Family, and Industry Job Skills and Competency Data for more than 15,000 Job Titles Skills Library

Not the job you're looking for? Here are some other Computational Chemist jobs in the San Diego, CA area that may be a better fit.

Computational Chemist

debutbiotech25, San Diego, CA

Chemist

Ashlynn Marketing Group, Santee, CA

AI Assistant is available now!

Feel free to start your new journey!